Suppression of renal crystal formation, inflammation, and fibrosis by blocking oncostatin M receptor β signaling
Abstract Oncostatin M (OSM) has pleiotropic effects on various inflammatory diseases, including kidney stone disease. The prevalence of kidney stones has increased worldwide, despite recent therapeutic advances, due to its high recurrence rate, suggesting the importance of prevention of repeated rec...
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Main Authors: | Ryusuke Deguchi, Tadasuke Komori, Shimpei Yamashita, Tomoko Hisaoka, Mizuki Kajimoto, Yasuo Kohjimoto, Isao Hara, Yoshihiro Morikawa |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-80411-4 |
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