Preclinical safety assessment in rats after dermal exposure to acetylcarvacrol, a potential acaricide against the brown dog tick

Preclinical safety assessment in rats after dermal exposure to acetylcarvacrol, a potential acaricide against the brown dog tick

Carvacrol, a phenolic monoterpene found in essential oils of plants of the Lamiaceae family, emerges as an alternative acaricide of plant origin. Its acetylation was proposed to obtain a derivative compound with a better pharmacological profile and lower toxicity to non-target organisms. The present...

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Main Authors: Graziela Hermínia Andrade Mendonça, Aline Chaves Reis, Isaac Filipe Moreira Konig, Gabriela Pereira Brito, José Henrique Silva Rodrigues, Camila Souza de Oliveira Guimarães, Vitor Luís Tenório Mati, Rafael Neodini Remedio
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Toxicology Reports
Subjects:
Semi-synthetic
Dermal toxicity
Acaricide
Tick control
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024002178
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