Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)

Abstract Background This study reports a rare case of delayed spontaneous resolution of double anterior chambers (AC) resulting from non-rhegmatogenous Descemet membrane detachment (DMD) after deep anterior lamellar keratoplasty (DALK). Currently, management guidelines for this condition have not be...

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Main Authors: Poramaporn Luangprasert, Passara Jongkhajornpong, Kaevalin Lekhanont, Manachai Nonpassopon, Varintorn Chuckpaiwong
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-024-03819-6
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author Poramaporn Luangprasert
Passara Jongkhajornpong
Kaevalin Lekhanont
Manachai Nonpassopon
Varintorn Chuckpaiwong
author_facet Poramaporn Luangprasert
Passara Jongkhajornpong
Kaevalin Lekhanont
Manachai Nonpassopon
Varintorn Chuckpaiwong
author_sort Poramaporn Luangprasert
collection DOAJ
description Abstract Background This study reports a rare case of delayed spontaneous resolution of double anterior chambers (AC) resulting from non-rhegmatogenous Descemet membrane detachment (DMD) after deep anterior lamellar keratoplasty (DALK). Currently, management guidelines for this condition have not been established. Case presentation A 65-year-old woman with lattice corneal dystrophy underwent uncomplicated DALK, during which an unrecognized type 2 big bubble was present. On postoperative day 1, a total DMD was observed, and descemetopexy was attempted. After an unsuccessful air-filled descemetopexy, we opted for observation without further intervention. Spontaneous reattachment of Descemet membrane with a clear cornea was achieved at 3 months postoperatively. The endothelial cell count was 2,165 cells/ mm2. Conclusions The spontaneous resolution of double AC in patients with DMD without visible perforation after DALK suggests that a “wait and observe” approach can be a reasonable and effective management strategy.
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institution Kabale University
issn 1471-2415
language English
publishDate 2024-12-01
publisher BMC
record_format Article
series BMC Ophthalmology
spelling doaj-art-79d0a980bc094c869f744ccbfa2367a72025-01-05T12:11:54ZengBMCBMC Ophthalmology1471-24152024-12-012411610.1186/s12886-024-03819-6Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)Poramaporn Luangprasert0Passara Jongkhajornpong1Kaevalin Lekhanont2Manachai Nonpassopon3Varintorn Chuckpaiwong4Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityAbstract Background This study reports a rare case of delayed spontaneous resolution of double anterior chambers (AC) resulting from non-rhegmatogenous Descemet membrane detachment (DMD) after deep anterior lamellar keratoplasty (DALK). Currently, management guidelines for this condition have not been established. Case presentation A 65-year-old woman with lattice corneal dystrophy underwent uncomplicated DALK, during which an unrecognized type 2 big bubble was present. On postoperative day 1, a total DMD was observed, and descemetopexy was attempted. After an unsuccessful air-filled descemetopexy, we opted for observation without further intervention. Spontaneous reattachment of Descemet membrane with a clear cornea was achieved at 3 months postoperatively. The endothelial cell count was 2,165 cells/ mm2. Conclusions The spontaneous resolution of double AC in patients with DMD without visible perforation after DALK suggests that a “wait and observe” approach can be a reasonable and effective management strategy.https://doi.org/10.1186/s12886-024-03819-6Double anterior chambersDescemet membrane detachmentDeep anterior lamellar keratoplastyDescemetopexy
spellingShingle Poramaporn Luangprasert
Passara Jongkhajornpong
Kaevalin Lekhanont
Manachai Nonpassopon
Varintorn Chuckpaiwong
Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)
BMC Ophthalmology
Double anterior chambers
Descemet membrane detachment
Deep anterior lamellar keratoplasty
Descemetopexy
title Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)
title_full Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)
title_fullStr Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)
title_full_unstemmed Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)
title_short Delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty (DALK)
title_sort delayed spontaneous resolution of a double anterior chamber following deep anterior lamellar keratoplasty dalk
topic Double anterior chambers
Descemet membrane detachment
Deep anterior lamellar keratoplasty
Descemetopexy
url https://doi.org/10.1186/s12886-024-03819-6
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AT passarajongkhajornpong delayedspontaneousresolutionofadoubleanteriorchamberfollowingdeepanteriorlamellarkeratoplastydalk
AT kaevalinlekhanont delayedspontaneousresolutionofadoubleanteriorchamberfollowingdeepanteriorlamellarkeratoplastydalk
AT manachainonpassopon delayedspontaneousresolutionofadoubleanteriorchamberfollowingdeepanteriorlamellarkeratoplastydalk
AT varintornchuckpaiwong delayedspontaneousresolutionofadoubleanteriorchamberfollowingdeepanteriorlamellarkeratoplastydalk