AIM2 promotes excitatory glutamate receptor expression by inhibiting STING and contributes to bone cancer pain in male mice

Abstract Bone cancer pain (BCP) is a common clinical problem in cancer patients. The plasticity of excitatory neurons within the spinal dorsal horn plays a significant role in the development of BCP. This study explored the roles of absent in melanoma 2 (AIM2) and stimulator of interferon gene (STIN...

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Bibliographic Details
Main Authors: Linhan Wang, Xueqin Xu, Shanchun Su, Biyun Li, Kunyu Zhang, Xiuqin Yu, Yangqiao Xiao, Shuangshuang Lu, Zihao Lu, Yanqiong Wu, Changbin Ke
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-83027-w
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