<i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds

Context: <i>Schinus terebinthifolia</i> Raddi is used in Brazilian folk medicine due to the wound healing and antiseptic properties of its bark, and its fruit are used as a condiment. However, the aerial parts of this plant have been studied and present some bioactive compounds as well....

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Main Authors: Mara Junqueira Carneiro, Guilherme Perez Pinheiro, Elisa Ribeiro Miranda Antunes, Leandro Wang Hantao, Thomas Moritz, Alexandra Christine Helena Frankland Sawaya
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Metabolites
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Online Access:https://www.mdpi.com/2218-1989/14/11/612
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author Mara Junqueira Carneiro
Guilherme Perez Pinheiro
Elisa Ribeiro Miranda Antunes
Leandro Wang Hantao
Thomas Moritz
Alexandra Christine Helena Frankland Sawaya
author_facet Mara Junqueira Carneiro
Guilherme Perez Pinheiro
Elisa Ribeiro Miranda Antunes
Leandro Wang Hantao
Thomas Moritz
Alexandra Christine Helena Frankland Sawaya
author_sort Mara Junqueira Carneiro
collection DOAJ
description Context: <i>Schinus terebinthifolia</i> Raddi is used in Brazilian folk medicine due to the wound healing and antiseptic properties of its bark, and its fruit are used as a condiment. However, the aerial parts of this plant have been studied and present some bioactive compounds as well. Objectives: The aim of this study was to investigate the variation in volatile and non-volatile composition of <i>S. terebinthifolia</i> leaves using untargeted metabolomics. Material and Methods: The leaves of four trees were collected over one year; ethanolic extracts were analyzed by UHPLC-MS and fresh leaves were analyzed by GC-MS using HS-SPME. The data were processed using online software. Results: The results suggest seasonality interfered little with the chemical composition of leaves. On the other hand, the sex of the plant clearly determined the chemical composition of both volatile and non-volatile compounds. Discussion and conclusions: Chemical variability between plants with male and female flowers is fundamental information for the standardized use of its leaves. Compounds with important biological activities were putatively identified, confirming the potential use of <i>S. terebinthifolia</i> leaves as a source of bioactive compounds, reducing waste and increasing economic gains for local farmers throughout the year.
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spelling doaj-art-794f076b430d42c597ea46befe417e1b2024-11-26T18:13:09ZengMDPI AGMetabolites2218-19892024-11-01141161210.3390/metabo14110612<i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile CompoundsMara Junqueira Carneiro0Guilherme Perez Pinheiro1Elisa Ribeiro Miranda Antunes2Leandro Wang Hantao3Thomas Moritz4Alexandra Christine Helena Frankland Sawaya5LabMetaMass, Faculty of Pharmaceutical Science, State University of Campinas, Campinas 13083-871, SP, BrazilInstitute of Biology, State University of Campinas, Campinas 13083-871, SP, BrazilInstitute of Biology, State University of Campinas, Campinas 13083-871, SP, BrazilInstitute of Chemistry, State University of Campinas, Campinas 13083-871, SP, BrazilDepartment of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 750 07 Umeå, SwedenLabMetaMass, Faculty of Pharmaceutical Science, State University of Campinas, Campinas 13083-871, SP, BrazilContext: <i>Schinus terebinthifolia</i> Raddi is used in Brazilian folk medicine due to the wound healing and antiseptic properties of its bark, and its fruit are used as a condiment. However, the aerial parts of this plant have been studied and present some bioactive compounds as well. Objectives: The aim of this study was to investigate the variation in volatile and non-volatile composition of <i>S. terebinthifolia</i> leaves using untargeted metabolomics. Material and Methods: The leaves of four trees were collected over one year; ethanolic extracts were analyzed by UHPLC-MS and fresh leaves were analyzed by GC-MS using HS-SPME. The data were processed using online software. Results: The results suggest seasonality interfered little with the chemical composition of leaves. On the other hand, the sex of the plant clearly determined the chemical composition of both volatile and non-volatile compounds. Discussion and conclusions: Chemical variability between plants with male and female flowers is fundamental information for the standardized use of its leaves. Compounds with important biological activities were putatively identified, confirming the potential use of <i>S. terebinthifolia</i> leaves as a source of bioactive compounds, reducing waste and increasing economic gains for local farmers throughout the year.https://www.mdpi.com/2218-1989/14/11/612pink pepper<i>Aroeira</i>UHPLC-MSGC-MSseasonalityplant sex
spellingShingle Mara Junqueira Carneiro
Guilherme Perez Pinheiro
Elisa Ribeiro Miranda Antunes
Leandro Wang Hantao
Thomas Moritz
Alexandra Christine Helena Frankland Sawaya
<i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds
Metabolites
pink pepper
<i>Aroeira</i>
UHPLC-MS
GC-MS
seasonality
plant sex
title <i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds
title_full <i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds
title_fullStr <i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds
title_full_unstemmed <i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds
title_short <i>Schinus terebinthifolia</i> Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds
title_sort i schinus terebinthifolia i raddi untargeted metabolomics approach to investigate the chemical variation in volatile and non volatile compounds
topic pink pepper
<i>Aroeira</i>
UHPLC-MS
GC-MS
seasonality
plant sex
url https://www.mdpi.com/2218-1989/14/11/612
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