Echinochrome A inhibits epithelial–mesenchymal transition and induces cell death mediated by DNA damage in human triple-negative breast cancer cells

Echinochrome A inhibits epithelial–mesenchymal transition and induces cell death mediated by DNA damage in human triple-negative breast cancer cells

Echinochrome A (Ech A), a marine-derived compound from Scaphechinus mirabilis, is known for its potent antioxidant activity. Its pharmacological derivative, Histochrome, is used to treat ischemia and cardiovascular disorders. Triple-negative breast cancer (TNBC) is an aggressive subtype with poor pr...

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Bibliographic Details
Main Authors: Soon Yong Park, Mi-So Jeong, Cong So Tran, Jinyoung Lee, Da-Young Eum, Seyeon Jung, Elena A. Vasileva, Seoung Rak Lee, Hyoung Kyu Kim, Natalia P. Mishchenko, Jin Han, Yoo Jin Choi, Si Ho Choi, Hwayoung Yun, Kyu Heo
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Journal of Functional Foods
Subjects:
Echinochrome A
Triple-negative breast cancer (TNBC)
Epithelial-mesenchymal transition (EMT)
DNA damage
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464625003354
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