Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient
Introduction The primary aim is to validate earlier suggested risk factors and to find new associated risk factors for (30-day) mortality after a hip fracture in the frail population. The secondary aim is to determine the factors associated with perioperative complications. At last we want to develo...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2020-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/10/9/e038988.full |
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| author | Louis de Jong Veronique van Rijckevorsel Taco M A L Klem Martijn Kuijper Gert R Roukema |
| author_facet | Louis de Jong Veronique van Rijckevorsel Taco M A L Klem Martijn Kuijper Gert R Roukema |
| author_sort | Louis de Jong |
| collection | DOAJ |
| description | Introduction The primary aim is to validate earlier suggested risk factors and to find new associated risk factors for (30-day) mortality after a hip fracture in the frail population. The secondary aim is to determine the factors associated with perioperative complications. At last we want to develop and validate a more specific 30-day mortality prediction tool compared with the Nottingham Hip Fracture Score. The 30-day mortality prediction can help inform surgical risk and guide shared decision-making among patients, family and physicians.Methods and analysis The study is designed as a prospective multicentre cohort study within the area of Rotterdam, the Netherlands starting from January 2018. All patients over 65 years of age, with an acute proximal hip fracture, are included. Treatment of patients will be by standard practice of care using the latest national and international guidelines. Inclusion will be continued at least until January 2021 and including at least 2500 patients. In this large cohort we hope to have sufficient strength and quality to identify risk factors of 30-day mortality and to compare them to known risk factors in literature. Moreover, we plan to develop and validate a 30-day mortality prediction tool, which identifies patients with a high probability of 30-day mortality.Ethics and dissemination Ethical approval for this protocol was given by the Ethics Committee of the Maasstad Hospital (TWOR). Patient data are stored anonymously using the Castor data management system. No external funding is used for this study. Results will be published in peer-reviewed publications and at international conferences.Trial registration number NL8313. |
| format | Article |
| id | doaj-art-7903fb2a480940168873f3c2343cf81d |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-7903fb2a480940168873f3c2343cf81d2025-01-08T12:15:09ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-038988Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patientLouis de Jong0Veronique van Rijckevorsel1Taco M A L Klem2Martijn Kuijper3Gert R Roukema4Department of Surgery, Maasstad Hospital, Rotterdam, The NetherlandsDepartment of Surgery, Maasstad Hospital, Rotterdam, The NetherlandsDepartment of Surgery, Franciscus Gasthuis en Vlietland, Rotterdam, The NetherlandsMaasstad Hospital, Rheumatology, Rotterdam, NetherlandsDepartment of Surgery, Maasstad Hospital, Rotterdam, The NetherlandsIntroduction The primary aim is to validate earlier suggested risk factors and to find new associated risk factors for (30-day) mortality after a hip fracture in the frail population. The secondary aim is to determine the factors associated with perioperative complications. At last we want to develop and validate a more specific 30-day mortality prediction tool compared with the Nottingham Hip Fracture Score. The 30-day mortality prediction can help inform surgical risk and guide shared decision-making among patients, family and physicians.Methods and analysis The study is designed as a prospective multicentre cohort study within the area of Rotterdam, the Netherlands starting from January 2018. All patients over 65 years of age, with an acute proximal hip fracture, are included. Treatment of patients will be by standard practice of care using the latest national and international guidelines. Inclusion will be continued at least until January 2021 and including at least 2500 patients. In this large cohort we hope to have sufficient strength and quality to identify risk factors of 30-day mortality and to compare them to known risk factors in literature. Moreover, we plan to develop and validate a 30-day mortality prediction tool, which identifies patients with a high probability of 30-day mortality.Ethics and dissemination Ethical approval for this protocol was given by the Ethics Committee of the Maasstad Hospital (TWOR). Patient data are stored anonymously using the Castor data management system. No external funding is used for this study. Results will be published in peer-reviewed publications and at international conferences.Trial registration number NL8313.https://bmjopen.bmj.com/content/10/9/e038988.full |
| spellingShingle | Louis de Jong Veronique van Rijckevorsel Taco M A L Klem Martijn Kuijper Gert R Roukema Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient BMJ Open |
| title | Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient |
| title_full | Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient |
| title_fullStr | Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient |
| title_full_unstemmed | Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient |
| title_short | Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient |
| title_sort | prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient |
| url | https://bmjopen.bmj.com/content/10/9/e038988.full |
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