SPL-108 mitigates metastasis and chemoresistance in tubo-ovarian carcinoma

SPL-108 mitigates metastasis and chemoresistance in tubo-ovarian carcinoma

Background: Overcoming the heterogeneous mechanisms of metastasis and chemoresistance will improve outcomes for women with tubo-ovarian carcinomas (TOCs). CD44 expression has been shown to be associated with poor prognosis and advanced disease in TOCs. In addition, studies have shown a link between...

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Bibliographic Details
Main Authors:	Olivia D. Lara, Elke Van Oudenhove, Luiza Pereira, Selim Misirlioglu, Douglas A. Levine, Kari E. Hacker
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Series:	Translational Oncology
Subjects:	Ovarian cancer Chemoresistance Metastasis Therapeutic approaches Targeted therapies
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523324002948
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