Identifying subtypes of longitudinal motor symptom severity trajectories in early Parkinson’s disease patients

Identifying subtypes of longitudinal motor symptom severity trajectories in early Parkinson’s disease patients

BackgroundMotor symptoms of Parkinson’s disease (PD) patients affect their ability of daily activities. Identifying distinct trajectories of motor symptom progression in PD patients can facilitate long-term management.MethodsA total of 155 PD patients were acquired from the Parkinson’s Disease Progr...

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Bibliographic Details
Main Authors: Xiaozhou Xu, Shushan Zhang, Chuanying Xu, Wei Zhang, Hui Zhao, Yumeng Liu, Shilei Zhai, Jie Zu, Zhining Li, Lishun Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neurology
Subjects:
Parkinson’s disease
motor symptoms
longitudinal trajectory
unsupervised clustering
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1597132/full
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