Pidotimod – Current Role and Evidence
Recurrent respiratory infections (RRIs) are common in the pediatric age group and in patients with chronic respiratory disorders, leading to frequent hospitalization and poorer quality of life. Studies have shown that an immature immune system in childhood can predispose to RRIs, leading to adult li...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Journal of Advanced Lung Health |
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| Online Access: | https://journals.lww.com/10.4103/jalh.jalh_36_24 |
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| _version_ | 1846136068844290048 |
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| author | Yash Sanjay Kedia Pranav Ish Vidushi Rathi |
| author_facet | Yash Sanjay Kedia Pranav Ish Vidushi Rathi |
| author_sort | Yash Sanjay Kedia |
| collection | DOAJ |
| description | Recurrent respiratory infections (RRIs) are common in the pediatric age group and in patients with chronic respiratory disorders, leading to frequent hospitalization and poorer quality of life. Studies have shown that an immature immune system in childhood can predispose to RRIs, leading to adult life. Immunomodulators are drugs which modulate the immune system of the host to increase resistance against various infections. They interact with specific receptors and cellular components of innate and adaptive response to modulate the immune response. Pidotimod (PDT) is one such immunomodulator which has shown emerging evidence in the past 2 decades, to reduce the recurrence of lower respiratory tract infections and help in faster recovery from the same. This review highlights the evidence behind the potential role of PDT in the prevention and management of RRIs. |
| format | Article |
| id | doaj-art-78cbfa3e6ecb4fe6b44f0f33c2c1d1d9 |
| institution | Kabale University |
| issn | 2772-7165 2772-7173 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Advanced Lung Health |
| spelling | doaj-art-78cbfa3e6ecb4fe6b44f0f33c2c1d1d92024-12-09T09:17:01ZengWolters Kluwer Medknow PublicationsJournal of Advanced Lung Health2772-71652772-71732024-11-01514710.4103/jalh.jalh_36_24Pidotimod – Current Role and EvidenceYash Sanjay KediaPranav IshVidushi RathiRecurrent respiratory infections (RRIs) are common in the pediatric age group and in patients with chronic respiratory disorders, leading to frequent hospitalization and poorer quality of life. Studies have shown that an immature immune system in childhood can predispose to RRIs, leading to adult life. Immunomodulators are drugs which modulate the immune system of the host to increase resistance against various infections. They interact with specific receptors and cellular components of innate and adaptive response to modulate the immune response. Pidotimod (PDT) is one such immunomodulator which has shown emerging evidence in the past 2 decades, to reduce the recurrence of lower respiratory tract infections and help in faster recovery from the same. This review highlights the evidence behind the potential role of PDT in the prevention and management of RRIs.https://journals.lww.com/10.4103/jalh.jalh_36_24immunostimulatorypidotimodrespiratory infections |
| spellingShingle | Yash Sanjay Kedia Pranav Ish Vidushi Rathi Pidotimod – Current Role and Evidence Journal of Advanced Lung Health immunostimulatory pidotimod respiratory infections |
| title | Pidotimod – Current Role and Evidence |
| title_full | Pidotimod – Current Role and Evidence |
| title_fullStr | Pidotimod – Current Role and Evidence |
| title_full_unstemmed | Pidotimod – Current Role and Evidence |
| title_short | Pidotimod – Current Role and Evidence |
| title_sort | pidotimod current role and evidence |
| topic | immunostimulatory pidotimod respiratory infections |
| url | https://journals.lww.com/10.4103/jalh.jalh_36_24 |
| work_keys_str_mv | AT yashsanjaykedia pidotimodcurrentroleandevidence AT pranavish pidotimodcurrentroleandevidence AT vidushirathi pidotimodcurrentroleandevidence |