Sensing Biomechanical Alterations in Red Blood Cells of Type 1 Diabetes Patients: Potential Markers for Microvascular Complications

Sensing Biomechanical Alterations in Red Blood Cells of Type 1 Diabetes Patients: Potential Markers for Microvascular Complications

In physiological conditions, red blood cells (RBCs) demonstrate remarkable deformability, allowing them to undergo considerable deformation when passing through the microcirculation. However, this deformability is compromised in Type 1 diabetes mellitus (T1DM) and related pathological conditions. Th...

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Main Authors: Riccardo Di Santo, Benedetta Niccolini, Alessandro Rizzi, Laura Bertini, Denise Pires Marafon, Maria Vaccaro, Federica Cristallo, Enrico Rosa, Linda Tartaglione, Laura Leo, Marco De Spirito, Gabriele Ciasca, Dario Pitocco
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biosensors
Subjects:
Atomic Force Microscopy
biomechanics
red blood cells
diabetes
microvascular complications
biomarkers
Online Access:https://www.mdpi.com/2079-6374/14/12/587
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