Curcumin encapsulated in PAMAM dendrimers for the therapeutic treatment of ischemic stroke in rats

Curcumin encapsulated in PAMAM dendrimers for the therapeutic treatment of ischemic stroke in rats

IntroductionIschemic stroke is a devastating neurovascular condition that occurs when cerebral tissue fails to receive an adequate supply of oxygen. Despite being a leading cause of death and disability worldwide, therapeutic interventions are currently limited. Polyamidoamine (PAMAM) dendrimers are...

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Main Authors: Justin Stadler, Lucas G. Garmo, David Doyle, Chin-I. Cheng, Garrett Richardson, Zain Waheed, Tim Tofan, Bhairavi Srinageshwar, Ajit Sharma, Robert B. Petersen, Gary L. Dunbar, Julien Rossignol
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
blood-brain barrier (BBB)
curcumin
ischemic stroke
neuroinflammation
PAMAM dendrimers
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1467417/full
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