The oral-gut microbiota axis: a link in cardiometabolic diseases
Abstract The oral-gut microbiota axis plays a crucial role in cardiometabolic health. This review explores the interactions between these microbiomes through enteric, hematogenous, and immune pathways, resulting in disruptions in microbial balance and metabolic processes. These disruptions contribut...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | npj Biofilms and Microbiomes |
| Online Access: | https://doi.org/10.1038/s41522-025-00646-5 |
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| _version_ | 1841544928833830912 |
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| author | Qian Xu Wenting Wang Yiwen Li Jing Cui Mengmeng Zhu Yanfei Liu Yue Liu |
| author_facet | Qian Xu Wenting Wang Yiwen Li Jing Cui Mengmeng Zhu Yanfei Liu Yue Liu |
| author_sort | Qian Xu |
| collection | DOAJ |
| description | Abstract The oral-gut microbiota axis plays a crucial role in cardiometabolic health. This review explores the interactions between these microbiomes through enteric, hematogenous, and immune pathways, resulting in disruptions in microbial balance and metabolic processes. These disruptions contribute to systemic inflammation, metabolic disorders, and endothelial dysfunction, which are closely associated with cardiometabolic diseases. Understanding these interactions provides insights for innovative therapeutic strategies to prevent and manage cardiometabolic diseases. |
| format | Article |
| id | doaj-art-789d8148ec71403882c9e1d5d4f2f0bd |
| institution | Kabale University |
| issn | 2055-5008 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Biofilms and Microbiomes |
| spelling | doaj-art-789d8148ec71403882c9e1d5d4f2f0bd2025-01-12T12:10:05ZengNature Portfolionpj Biofilms and Microbiomes2055-50082025-01-0111111310.1038/s41522-025-00646-5The oral-gut microbiota axis: a link in cardiometabolic diseasesQian Xu0Wenting Wang1Yiwen Li2Jing Cui3Mengmeng Zhu4Yanfei Liu5Yue Liu6National Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical SciencesNational Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical SciencesNational Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical SciencesNational Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical SciencesNational Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical SciencesNational Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical SciencesNational Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical SciencesAbstract The oral-gut microbiota axis plays a crucial role in cardiometabolic health. This review explores the interactions between these microbiomes through enteric, hematogenous, and immune pathways, resulting in disruptions in microbial balance and metabolic processes. These disruptions contribute to systemic inflammation, metabolic disorders, and endothelial dysfunction, which are closely associated with cardiometabolic diseases. Understanding these interactions provides insights for innovative therapeutic strategies to prevent and manage cardiometabolic diseases.https://doi.org/10.1038/s41522-025-00646-5 |
| spellingShingle | Qian Xu Wenting Wang Yiwen Li Jing Cui Mengmeng Zhu Yanfei Liu Yue Liu The oral-gut microbiota axis: a link in cardiometabolic diseases npj Biofilms and Microbiomes |
| title | The oral-gut microbiota axis: a link in cardiometabolic diseases |
| title_full | The oral-gut microbiota axis: a link in cardiometabolic diseases |
| title_fullStr | The oral-gut microbiota axis: a link in cardiometabolic diseases |
| title_full_unstemmed | The oral-gut microbiota axis: a link in cardiometabolic diseases |
| title_short | The oral-gut microbiota axis: a link in cardiometabolic diseases |
| title_sort | oral gut microbiota axis a link in cardiometabolic diseases |
| url | https://doi.org/10.1038/s41522-025-00646-5 |
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