Current status of treatment for malignant ovarian sex cord-stromal tumors

Abstract Malignant ovarian sex cord-stromal tumors belong to a specific type of ovarian epithelial carcinoma, and their prognosis is related to the kind of pathology. Unlike epithelial ovarian cancer, most malignant ovarian sex cord-stromal tumors are low-grade malignant and have a good prognosis. S...

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Bibliographic Details
Main Authors: Fang Chunli, Chen Hailin, Zhou Yingying, Xiao Huajing, Xu Boqun
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-024-01687-6
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Summary:Abstract Malignant ovarian sex cord-stromal tumors belong to a specific type of ovarian epithelial carcinoma, and their prognosis is related to the kind of pathology. Unlike epithelial ovarian cancer, most malignant ovarian sex cord-stromal tumors are low-grade malignant and have a good prognosis. Still, they have a tendency to recur in the long term, and the mortality rate of patients after recurrence is high. Surgery is the preferred treatment for malignant ovarian sex cord-stromal tumors with chemotherapy, and other comprehensive treatments. Recurrent and metastatic malignant ovarian sex cord-stromal tumors usually require systemic adjuvant chemotherapy, and hormonal or targeted therapy may be attempted on an individualized basis in cases where chemotherapy fails.
ISSN:2730-6011