Astaxanthin-rich Nannochloropsis oculata mitigates high-fat diet-induced liver dysfunction in zebrafish by modulating lipid metabolism and oxidative stress

Astaxanthin-rich Nannochloropsis oculata mitigates high-fat diet-induced liver dysfunction in zebrafish by modulating lipid metabolism and oxidative stress

Abstract High-fat diets (HFDs) are widely used in aquaculture but may adversely affect fish liver health by disturbing lipid metabolism and promoting oxidative stress. This study investigated the protective effects of Nannochloropsis oculata enriched with astaxanthin on zebrafish (Danio rerio) fed a...

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Bibliographic Details
Main Authors: Shima Jafari, Mohammad Akhavan-Bahabadi, Seyed Pezhman Hosseini Shekarabi, Mehdi Shamsaie Mehrgan, Elly Lowen, Kasra Lotfi, Azin Azari
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Microalgae
High-fat diet
Liver health
Lipid metabolism
Inflammation
Online Access:https://doi.org/10.1038/s41598-025-13642-8
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