Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment

Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment

Abstract Staphylococcus aureus can cause outbreaks and becomes multi-drug resistant through gene mutations and acquiring resistance genes. However, why S. aureus easily adapts to hospital environments, promoting resistance and recurrent infections, remains unknown. Here we show that a specific S. au...

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Main Authors: Yuriko Yamazaki, Tomoka Ito, Seitaro Nakagawa, Takashi Sugihira, Chinami Kurita-Tachibana, Amer E. Villaruz, Kensuke Ishiguro, Barbora Salcman, Shuo Li, Sanami Takada, Naohiro Inohara, Yoko Kusuya, Aki Shibata, Masakazu Tamai, Reika Aoyama, Kanako Inoue, Shota Murata, Kazuyuki Matsushita, Akiko Miyabe, Toshibumi Taniguchi, Hidetoshi Igari, Naruhiko Ishiwada, Masateru Taniguchi, Taka-Aki Nakada, Hiroyuki Matsue, Manabu Fujimoto, Haruka Hishiki, Yoshiteru Osone, Hiromichi Hamada, Naoki Shimojo, Tsutomu Suzuki, Michael Otto, Gabriel Núñez, Hiroki Takahashi, Akiko Takaya, Yuumi Nakamura
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54033-3
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