Cell-Based Glioma Models for Anticancer Drug Screening: From Conventional Adherent Cell Cultures to Tumor-Specific Three-Dimensional Constructs

Cell-Based Glioma Models for Anticancer Drug Screening: From Conventional Adherent Cell Cultures to Tumor-Specific Three-Dimensional Constructs

Gliomas are a group of primary brain tumors characterized by their aggressive nature and resistance to treatment. Infiltration of surrounding normal tissues limits surgical approaches, wide inter- and intratumor heterogeneity hinders the development of universal therapeutics, and the presence of the...

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Bibliographic Details
Main Authors: Daria Lanskikh, Olga Kuziakova, Ivan Baklanov, Alina Penkova, Veronica Doroshenko, Ivan Buriak, Valeriia Zhmenia, Vadim Kumeiko
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
glioma
three-dimensional model
brain tumors
cancer
genetically modified model
cell-based screening
Online Access:https://www.mdpi.com/2073-4409/13/24/2085
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