Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic rats
Java bark ( Lannea coromandelica (Houtt.) Merr.) is used traditionally to heal wounds. In this research, nanogel made from Javanese wood bark extract (EKBKJ) was tested to see its ability to heal wounds in diabetic mice. EKBKJ nanogels were made in three different concentrations: 1%, 4%, and 7%, and...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2024-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_04008.pdf |
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| author | Jumaldi Syamsy Salsabilla Riasty Putri Nafilah Arta Dwi Sibadu Annisa Awalia Rahma MH Febriansyah M. Chandra Widyaningsih Wahyu Yuliani Sapto |
| author_facet | Jumaldi Syamsy Salsabilla Riasty Putri Nafilah Arta Dwi Sibadu Annisa Awalia Rahma MH Febriansyah M. Chandra Widyaningsih Wahyu Yuliani Sapto |
| author_sort | Jumaldi Syamsy Salsabilla Riasty Putri |
| collection | DOAJ |
| description | Java bark (
Lannea coromandelica (Houtt.) Merr.) is used traditionally to heal wounds. In this research, nanogel made from Javanese wood bark extract (EKBKJ) was tested to see its ability to heal wounds in diabetic mice. EKBKJ nanogels were made in three different concentrations: 1%, 4%, and 7%, and tested to see their physical properties such as particle size, pH, dispersing ability, and adhesiveness. The EKBKJ nanogel activity test was carried out on six groups of mice for 14 days by monitoring the level of wound healing and visual appearance of the wound. The results showed that the three types of EKBKJ nanogel met nanogel quality standards, with 1%, 4%, and 7% nanogel able to heal wounds better than gel base in diabetic mice (p<0.05). Furthermore, 1% EKBKJ nanogel showed significantly higher healing rate compared with 4% and 7% EKBKJ nanogel. Thus, it can be concluded that 1% EKBKJ nanogel has a better effect on healing diabetic wounds. |
| format | Article |
| id | doaj-art-77fae8c3723c49fbadf3e1e47fc20a13 |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-77fae8c3723c49fbadf3e1e47fc20a132025-01-16T11:19:46ZengEDP SciencesBIO Web of Conferences2117-44582024-01-011480400810.1051/bioconf/202414804008bioconf_icobeaf2024_04008Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic ratsJumaldi Syamsy Salsabilla Riasty Putri0Nafilah Arta Dwi1Sibadu Annisa Awalia Rahma MH2Febriansyah M. Chandra3Widyaningsih Wahyu4Yuliani Sapto5Faculty of Pharmacy, Universitas Ahmad DahlanFaculty of Pharmacy, Universitas Ahmad DahlanFaculty of Pharmacy, Universitas Ahmad DahlanFaculty of Pharmacy, Universitas Ahmad DahlanFaculty of Pharmacy, Universitas Ahmad DahlanFaculty of Pharmacy, Universitas Ahmad DahlanJava bark ( Lannea coromandelica (Houtt.) Merr.) is used traditionally to heal wounds. In this research, nanogel made from Javanese wood bark extract (EKBKJ) was tested to see its ability to heal wounds in diabetic mice. EKBKJ nanogels were made in three different concentrations: 1%, 4%, and 7%, and tested to see their physical properties such as particle size, pH, dispersing ability, and adhesiveness. The EKBKJ nanogel activity test was carried out on six groups of mice for 14 days by monitoring the level of wound healing and visual appearance of the wound. The results showed that the three types of EKBKJ nanogel met nanogel quality standards, with 1%, 4%, and 7% nanogel able to heal wounds better than gel base in diabetic mice (p<0.05). Furthermore, 1% EKBKJ nanogel showed significantly higher healing rate compared with 4% and 7% EKBKJ nanogel. Thus, it can be concluded that 1% EKBKJ nanogel has a better effect on healing diabetic wounds.https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_04008.pdf |
| spellingShingle | Jumaldi Syamsy Salsabilla Riasty Putri Nafilah Arta Dwi Sibadu Annisa Awalia Rahma MH Febriansyah M. Chandra Widyaningsih Wahyu Yuliani Sapto Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic rats BIO Web of Conferences |
| title | Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic rats |
| title_full | Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic rats |
| title_fullStr | Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic rats |
| title_full_unstemmed | Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic rats |
| title_short | Nanogel activity of java bark extract (lannea coromandelica (houtt.) merr.) as wound healing in diabetic rats |
| title_sort | nanogel activity of java bark extract lannea coromandelica houtt merr as wound healing in diabetic rats |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_04008.pdf |
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