Decreased expression of LEF1 caused defective decidualization by inhibiting IL-11 expression in patients with adenomyosis

Decreased expression of LEF1 caused defective decidualization by inhibiting IL-11 expression in patients with adenomyosis

Abstract Reduced lymphoid enhancer-binding factor 1 (LEF1) expression in patients with adenomyosis during the mid-secretory phase leads to impaired endometrial receptivity, affecting embryo implantation. This study investigated the molecular mechanisms underlying reduced endometrial receptivity in 2...

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Bibliographic Details
Main Authors: Jingru Duan, Xiaowei Zhou, Hanfei Zhu, Mingjuan Zhou, Mengyu Liu, Yan Zhou, Wenzhu Li, Bufang Xu, Aijun Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
Adenomyosis
LEF1
IL-11
Endometrial receptivity
Endometrial decidualization
Online Access:https://doi.org/10.1186/s10020-024-01054-9
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