Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia

Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia

Not available.

Saved in:

Bibliographic Details
Main Authors:	Yixiao Mo, Qi Zhang, Miao Wang, Jihui Chen, Wenting Hu, Changcheng Chen, Yanjing Tang, Zhuo Wang, Jingjing Wang, Xiaoxiao Chen, Shuhong Shen
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2025-01-01
Series:	Haematologica
Online Access:	https://haematologica.org/article/view/11905
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Osteoporosis in Acute Lymphoblastic Leukemia
by: Lestry Fibriani, et al.
Published: (2019-09-01)

Relapsed childhood T-cell acute lymphoblastic leukemia and lymphoblastic lymphoma
by: Andrew D. Hughes, et al.
Published: (2025-01-01)

The Determination of Partition Coefficient of 6-Mercaptopurine Derivatives by Thin Layer Chromatography
by: Andrzej Czyrski, et al.
Published: (2013-01-01)

In vivo monitoring of leukemia-niche interactions in a zebrafish xenograft model.
by: Anja Arner, et al.
Published: (2024-01-01)

The combination of a tyrosine kinase inhibitor and blinatumomab in patients with Philadelphia chromosome–positive acute lymphoblastic leukemia or Philadelphia chromosome‐like acute lymphoblastic leukemia
by: Xiaoxia Wu, et al.
Published: (2024-09-01)

Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models
by: Pallavi Sontakke, et al.
Published: (2016-01-01)

Differential Regulation of NK Cell Receptors in Acute Lymphoblastic Leukemia
by: Le Jie Lee, et al.
Published: (2022-01-01)

Acute Lymphoblastic Leukemia Arising in CALR Mutated Essential Thrombocythemia
by: Stephen E. Langabeer, et al.
Published: (2016-01-01)

Flow Cytometric DNA Index and Karyotype in Childhood Lymphoblastic Leukemia
by: Erik Forestier, et al.
Published: (1998-01-01)

Successful Treatment of Fanconi Anemia and T-Cell Acute Lymphoblastic Leukemia
by: Terrie Flatt, et al.
Published: (2012-01-01)

Relapsed Acute Lymphoblastic Leukemia Presenting as Acute Renal Failure
by: Ashley Rose, et al.
Published: (2019-01-01)

An Adult Patient with Systemic Mastocytosis and B-Acute Lymphoblastic Leukemia
by: Theodoros Iliakis, et al.
Published: (2014-01-01)

Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia
by: Fabian Lang, et al.
Published: (2015-01-01)

Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression
by: Georgia Tsaouli, et al.
Published: (2019-01-01)

CAR-T CELL THERAPY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
by: Ugo Testa, et al.
Published: (2024-01-01)

Secondary neoplasms in survivors of pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma: a single-center, retrospective study
by: Eri Ushida, et al.
Published: (2025-01-01)

Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomics
by: Yin Le, et al.
Published: (2025-01-01)

DRESSed for distress: a case of allopurinol-induced DRESS syndrome
by: Areti Kalfoutzou, et al.
Published: (2024-12-01)

Adherence to Azathioprine/6-Mercaptopurine in Children and Adolescents with Inflammatory Bowel Diseases: A Multimethod Study
by: Mervat M. Alsous, et al.
Published: (2020-01-01)

Acute Neurotoxicity in Children Treated for Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma: A 10-Year Single-Centre Experience
by: Izabela Kranjčec, et al.
Published: (2024-12-01)

Venetoclax plus low-intensity chemotherapy for adults with acute lymphoblastic leukemia
by: Marlise R. Luskin, et al.
Published: (2025-02-01)

The mitochondria as an emerging target of self-renewal in T-cell acute lymphoblastic leukemia
by: Majd A. Al-Hamaly, et al.
Published: (2025-12-01)

Early T-Cell Precursor Leukemia Has a Higher Risk of Induction-Related Infection among T-Cell Acute Lymphoblastic Leukemia in Adult
by: Kangyu Huang, et al.
Published: (2020-01-01)

Molecular and pharmacological heterogeneity of ETV6::RUNX1 acute lymphoblastic leukemia
by: Zhenhua Li, et al.
Published: (2025-01-01)

Bilateral Facial Paralysis and Deafness in a Child Treated for Acute Lymphoblastic Leukemia
by: Rafael V. Lucena, et al.
Published: (2019-01-01)

Skin Nodules in a 16-Year-Old Adolescent with Acute Lymphoblastic Leukemia
by: Amanda Ruth, et al.
Published: (2009-01-01)

T-Cell Lymphoblastic Leukemia/Lymphoma: Relapse 16 Years after First Remission
by: Lauren Elreda, et al.
Published: (2014-01-01)

Deep and Machine Learning for Acute Lymphoblastic Leukemia Diagnosis: A Comprehensive Review
by: Mohammad Faiz, et al.
Published: (2024-07-01)

Catecholamine Secretory Tumors, Should Acute Lymphoblastic Leukemia be Included Under this Paradigm?
by: Antoine Fakhry AbdelMassih, et al.
Published: (2024-12-01)

Value of routine blood count surveillance in detecting relapse in acute lymphoblastic leukemia
by: Sarah AlHarbi, et al.
Published: (2025-01-01)

Survival in patients with acute non-lymphoblastic leukemia at the "Dr. Gustavo Aldereguía Lima". Hospital. A ten years experience
by: Rafael Alejandro Gómez Baute, et al.
Published: (2010-11-01)

Identification of a novel TOP2B::AFF2 fusion gene in B-cell acute lymphoblastic leukemia
by: Tao Liu, et al.
Published: (2025-01-01)

Comparison of Febuxostat and Allopurinol in the Treatment of Patients with Chronic Kidney Disease Stage 3∼5 with Hyperuricemia
by: Zhimin Liao, et al.
Published: (2022-01-01)

Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia
by: Oreoluwa Oladiran, et al.
Published: (2018-01-01)

Vitamin E and N-Acetylcysteine as Antioxidant Adjuvant Therapy in Children with Acute Lymphoblastic Leukemia
by: Youssef Al-Tonbary, et al.
Published: (2009-01-01)

Systemic xanthogranuloma involving bone marrow and skin in a case of B-Lymphoblastic Leukemia
by: Manasi C. Mundada, et al.
Published: (2023-01-01)

Acute Lymphoblastic Leukemia Presenting as Pituitary Apoplexy: A Case Report and Review of the Literature
by: Rahul Gupta, et al.
Published: (2021-01-01)

Association of killer immunoglobulin-like receptor genotypes and haplotypes with acute lymphoblastic leukemia risk
by: Jameel Al-Tamimi, et al.
Published: (2025-01-01)

Diagnostic utility of LMO2 immunohistochemistry in distinguishing T-lymphoblastic leukemia/lymphoma from thymoma
by: Divya Bansal, et al.
Published: (2023-01-01)

A Novel Method for Preparation of Carrageenan/Fish Scale Collagen/Allopurinol Biocomposite Film
by: Quoc Manh Vu, et al.
Published: (2021-01-01)