Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia

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Main Authors: Yixiao Mo, Qi Zhang, Miao Wang, Jihui Chen, Wenting Hu, Changcheng Chen, Yanjing Tang, Zhuo Wang, Jingjing Wang, Xiaoxiao Chen, Shuhong Shen
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11905
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author Yixiao Mo
Qi Zhang
Miao Wang
Jihui Chen
Wenting Hu
Changcheng Chen
Yanjing Tang
Zhuo Wang
Jingjing Wang
Xiaoxiao Chen
Shuhong Shen
author_facet Yixiao Mo
Qi Zhang
Miao Wang
Jihui Chen
Wenting Hu
Changcheng Chen
Yanjing Tang
Zhuo Wang
Jingjing Wang
Xiaoxiao Chen
Shuhong Shen
author_sort Yixiao Mo
collection DOAJ
description Not available.
format Article
id doaj-art-774d81abd3c442a58dc94d0405ee7ed6
institution Kabale University
issn 0390-6078
1592-8721
language English
publishDate 2025-01-01
publisher Ferrata Storti Foundation
record_format Article
series Haematologica
spelling doaj-art-774d81abd3c442a58dc94d0405ee7ed62025-01-16T19:43:57ZengFerrata Storti FoundationHaematologica0390-60781592-87212025-01-01999110.3324/haematol.2024.286882Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemiaYixiao Mo0Qi Zhang1Miao Wang2Jihui Chen3Wenting Hu4Changcheng Chen5Yanjing Tang6Zhuo Wang7Jingjing Wang8Xiaoxiao Chen9Shuhong Shen10Department of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Department of Pediatrics, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, People’s Hospital of Henan University, Zhengzhou, Henan, ChinaDepartment of Clinical Pharmacy, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaCrown Bioscience, Inc., CA, USADepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Hematology/Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China Not available. https://haematologica.org/article/view/11905
spellingShingle Yixiao Mo
Qi Zhang
Miao Wang
Jihui Chen
Wenting Hu
Changcheng Chen
Yanjing Tang
Zhuo Wang
Jingjing Wang
Xiaoxiao Chen
Shuhong Shen
Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia
Haematologica
title Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia
title_full Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia
title_fullStr Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia
title_full_unstemmed Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia
title_short Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia
title_sort results from patient derived xenograft models support co administration of allopurinol and 6 mercaptopurine to reduce hepatotoxicity and improve event free survival in pediatric acute lymphoblastic leukemia
url https://haematologica.org/article/view/11905
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