Tumor-specific cytosol-penetrating antibodies for antigen- and TME-dependent intracellular cargo delivery
Although a considerable number of disease-related biomolecular interactions occur in the cytosol, therapeutic and diagnostic application of target-specific binding proteins is largely confined to surface-exposed or extracellular targets. Therefore, protein-cargo delivery approaches, including cell-p...
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Main Authors: | Carolin Sophie Dombrowsky, Felix Klaus Geyer, Diana Zakharchuk, Harald Kolmar |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
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Series: | Molecular Therapy: Oncology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2950329924001735 |
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