Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer

Abstract Background Co-occurring mutations in pairs of genes can pinpoint clinically relevant subgroups of cancer. Most colorectal cancers (CRCs) are microsatellite stable (MSS) and have few frequent mutations. Large patient cohorts and broad genomic coverage are needed for comprehensive co-mutation...

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Bibliographic Details
Main Authors: Luís Nunes, Jakob Mørkved Stenersen, Kushtrim Kryeziu, Tobias Sjöblom, Bengt Glimelius, Ragnhild A. Lothe, Anita Sveen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Cancer
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Online Access:https://doi.org/10.1186/s12943-024-02173-x
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