The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A review

Oral cancer as well as other Head and Neck cancer (HNC) patients face adverse effects because of the range of treatment and the possibility of treatment-related toxicity. This includes complications like skin desquamation, depression, mucositis, nausea and vomiting. It negatively impacts the Quality...

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Main Authors: Rishima Bhutani, Ravindra Singh, Anushka Mishra, Priya Baluni
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Oral Oncology Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S277290602400390X
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author Rishima Bhutani
Ravindra Singh
Anushka Mishra
Priya Baluni
author_facet Rishima Bhutani
Ravindra Singh
Anushka Mishra
Priya Baluni
author_sort Rishima Bhutani
collection DOAJ
description Oral cancer as well as other Head and Neck cancer (HNC) patients face adverse effects because of the range of treatment and the possibility of treatment-related toxicity. This includes complications like skin desquamation, depression, mucositis, nausea and vomiting. It negatively impacts the Quality of life (QoL) of HNC patients post-treatment. The goal of this study was to conduct a literature review on the occurrence of various difficulties, such as nutrition, functional status, psychological well-being and decreased QoL in post-chemoradiotherapy in head and neck cancer survivors, specifically oral cancer survivors. Databases like Google Search, Google Scholar, PubMed, Scopus, Web of Science and ScienceDirect were searched with keywords such as ‘Chemoradiotherapy’, ‘Chemotherapy’, ‘Radiotherapy’, ‘Oral cancer’ ‘Head and Neck Cancer’ and ‘QoL’ ‘Quality of life’. 30 research papers fulfilled the criteria of focusing on Oral cancer and HNC patients. The head and neck carcinomas are close to various bodily structures involved in vital physiological and social activities components. Thereupon the collateral damage commonly associated with disease treatment affects essential bodily functions and can have adverse consequences on the QoL of the patients. Patients receiving concurrent chemoradiotherapy experience such substantial side effects that it hampers their ability to finish their treatment cycle without pauses or dose modifications. Therefore, it is essential to monitor and prevent such effects from CRT. Psychological interventions, palliative care and other such efforts can help improve the QoL of Oral cancer patients.
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spelling doaj-art-76dcb0cf95c5437cb8f0e4b7f779da0a2025-01-09T06:16:42ZengElsevierOral Oncology Reports2772-90602024-06-0110100544The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A reviewRishima Bhutani0Ravindra Singh1Anushka Mishra2Priya Baluni3Department of Humanities & Social Sciences, Graphic Era (Deemed to be) University, Dehradun, 248002, Uttarakhand, India; Corresponding author.Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, IndiaDepartment of Humanities & Social Sciences, Graphic Era (Deemed to be) University, Dehradun, 248002, Uttarakhand, IndiaDepartment of Humanities & Social Sciences, Graphic Era (Deemed to be) University, Dehradun, 248002, Uttarakhand, IndiaOral cancer as well as other Head and Neck cancer (HNC) patients face adverse effects because of the range of treatment and the possibility of treatment-related toxicity. This includes complications like skin desquamation, depression, mucositis, nausea and vomiting. It negatively impacts the Quality of life (QoL) of HNC patients post-treatment. The goal of this study was to conduct a literature review on the occurrence of various difficulties, such as nutrition, functional status, psychological well-being and decreased QoL in post-chemoradiotherapy in head and neck cancer survivors, specifically oral cancer survivors. Databases like Google Search, Google Scholar, PubMed, Scopus, Web of Science and ScienceDirect were searched with keywords such as ‘Chemoradiotherapy’, ‘Chemotherapy’, ‘Radiotherapy’, ‘Oral cancer’ ‘Head and Neck Cancer’ and ‘QoL’ ‘Quality of life’. 30 research papers fulfilled the criteria of focusing on Oral cancer and HNC patients. The head and neck carcinomas are close to various bodily structures involved in vital physiological and social activities components. Thereupon the collateral damage commonly associated with disease treatment affects essential bodily functions and can have adverse consequences on the QoL of the patients. Patients receiving concurrent chemoradiotherapy experience such substantial side effects that it hampers their ability to finish their treatment cycle without pauses or dose modifications. Therefore, it is essential to monitor and prevent such effects from CRT. Psychological interventions, palliative care and other such efforts can help improve the QoL of Oral cancer patients.http://www.sciencedirect.com/science/article/pii/S277290602400390XChemoradiotherapyChemotherapyRadiotherapyOral cancerHead and neck cancerQuality of life
spellingShingle Rishima Bhutani
Ravindra Singh
Anushka Mishra
Priya Baluni
The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A review
Oral Oncology Reports
Chemoradiotherapy
Chemotherapy
Radiotherapy
Oral cancer
Head and neck cancer
Quality of life
title The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A review
title_full The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A review
title_fullStr The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A review
title_full_unstemmed The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A review
title_short The adverse impact of chemo-radiotherapy on the quality of life of oral cancer patients: A review
title_sort adverse impact of chemo radiotherapy on the quality of life of oral cancer patients a review
topic Chemoradiotherapy
Chemotherapy
Radiotherapy
Oral cancer
Head and neck cancer
Quality of life
url http://www.sciencedirect.com/science/article/pii/S277290602400390X
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