Infection with Toxoplasma gondii triggers coagulation at the blood-brain barrier and a reduction in cerebral blood flow

Infection with Toxoplasma gondii triggers coagulation at the blood-brain barrier and a reduction in cerebral blood flow

Abstract Background Immunothrombosis is the process by which the coagulation cascade interacts with the innate immune system to control infection. However, the formation of clots within the brain vasculature can be detrimental to the host. Recent work has demonstrated that Toxoplasma gondii infects...

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Bibliographic Details
Main Authors: Evelyn M. Hoover, Christine A. Schneider, Christian Crouzet, Tatiane S. Lima, Dario X. Figueroa Velez, Cuong J. Tran, Dritan Agalliu, Sunil P. Gandhi, Bernard Choi, Melissa B. Lodoen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Neuroinflammation
Subjects:
Toxoplasma gondii
CNS infection
Thrombosis
Cerebral blood flow
Blood-brain barrier
Online Access:https://doi.org/10.1186/s12974-024-03330-1
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