Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B
Chronic hepatitis B (CHB) is a high-risk condition that requires continuous monitoring and appropriate management during the natural course of the disease. In particular, the assessment of liver fibrosis is crucial for determining the optimal timing of antiviral therapy, evaluating the treatment res...
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| Format: | Article |
| Language: | English |
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Jin Publishing & Printing Co.
2024-11-01
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| Series: | The Korean Journal of Gastroenterology |
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| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=6060&vmd=Full |
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| _version_ | 1841561192578940928 |
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| author | Ye Ji Jun Minjong Lee Ho Soo Chun Tae Hun Kim |
| author_facet | Ye Ji Jun Minjong Lee Ho Soo Chun Tae Hun Kim |
| author_sort | Ye Ji Jun |
| collection | DOAJ |
| description | Chronic hepatitis B (CHB) is a high-risk condition that requires continuous monitoring and appropriate management during the natural course of the disease. In particular, the assessment of liver fibrosis is crucial for determining the optimal timing of antiviral therapy, evaluating the treatment response, and predicting the occurrence and prognosis of hepatocellular carcinoma (HCC) in the management of CHB. Although a liver biopsy is the gold standard for diagnosing liver inflammation, steatosis, and fibrosis, there has been
a growing trend in the use of non-invasive tests, such as serum biomarkers, transient elastography, and shear wave elastography in CHB patients. This review provides a summary of the key research findings on the use of serum biomarkers and transient elastography in assessing liver fibrosis, monitoring the disease progression, and predicting the prognosis of CHB patients, with an emphasis
on their clinical applicability. |
| format | Article |
| id | doaj-art-76ce4280eb3a4a8dab96c62ded84d15f |
| institution | Kabale University |
| issn | 1598-9992 2233-6869 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj-art-76ce4280eb3a4a8dab96c62ded84d15f2025-01-03T05:11:20ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692024-11-0184520621410.4166/kjg.2024.106Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis BYe Ji Jun0Minjong Lee1https://orcid.org/0000-0002-3159-5444Ho Soo Chun2Tae Hun Kim3Department of Internal Medicine, Ewha Womans University College of Medicine; Department of Internal Medicine, Ewha Womans University Seoul Hospital, Seoul, KoreaDepartment of Internal Medicine, Ewha Womans University College of Medicine; Department of Internal Medicine, Ewha Womans University Seoul Hospital, Seoul, KoreaDepartment of Internal Medicine, Ewha Womans University College of Medicine; Department of Internal Medicine, Ewha Womans University Seoul Hospital, Seoul, KoreaDepartment of Internal Medicine, Ewha Womans University College of Medicine; Department of Internal Medicine, Ewha Womans University Seoul Hospital, Seoul, KoreaChronic hepatitis B (CHB) is a high-risk condition that requires continuous monitoring and appropriate management during the natural course of the disease. In particular, the assessment of liver fibrosis is crucial for determining the optimal timing of antiviral therapy, evaluating the treatment response, and predicting the occurrence and prognosis of hepatocellular carcinoma (HCC) in the management of CHB. Although a liver biopsy is the gold standard for diagnosing liver inflammation, steatosis, and fibrosis, there has been a growing trend in the use of non-invasive tests, such as serum biomarkers, transient elastography, and shear wave elastography in CHB patients. This review provides a summary of the key research findings on the use of serum biomarkers and transient elastography in assessing liver fibrosis, monitoring the disease progression, and predicting the prognosis of CHB patients, with an emphasis on their clinical applicability.https://www.kjg.or.kr/journal/view.html?uid=6060&vmd=Fullchronic hepatitis bfibrosisliver cirrhosishepatocellular carcinoma |
| spellingShingle | Ye Ji Jun Minjong Lee Ho Soo Chun Tae Hun Kim Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B The Korean Journal of Gastroenterology chronic hepatitis b fibrosis liver cirrhosis hepatocellular carcinoma |
| title | Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B |
| title_full | Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B |
| title_fullStr | Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B |
| title_full_unstemmed | Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B |
| title_short | Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B |
| title_sort | non invasive test for assessment of liver fibrosis in chronic hepatitis b |
| topic | chronic hepatitis b fibrosis liver cirrhosis hepatocellular carcinoma |
| url | https://www.kjg.or.kr/journal/view.html?uid=6060&vmd=Full |
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