Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion

Hepatic ischemia/reperfusion injury is an important complication of liver surgery and transplantation. The mechanisms of this injury as well as the subsequent reparative and regenerative processes have been the subject of thorough study. In this paper, we discuss the complex and coordinated response...

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Main Author: Alex B. Lentsch
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.6064/2012/513192
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author Alex B. Lentsch
author_facet Alex B. Lentsch
author_sort Alex B. Lentsch
collection DOAJ
description Hepatic ischemia/reperfusion injury is an important complication of liver surgery and transplantation. The mechanisms of this injury as well as the subsequent reparative and regenerative processes have been the subject of thorough study. In this paper, we discuss the complex and coordinated responses leading to parenchymal damage after liver ischemia/reperfusion as well as the manner in which the liver clears damaged cells and regenerates functional mass.
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spelling doaj-art-769f5af4df9f4c64a16b03a8d9b3f6482025-02-03T05:53:07ZengWileyScientifica2090-908X2012-01-01201210.6064/2012/513192513192Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/ReperfusionAlex B. Lentsch0Department of Surgery, College of Medicine, University of Cincinnati, 231 Albert Sabin Way, ML 0558, Cincinnati, OH 45267-0558, USAHepatic ischemia/reperfusion injury is an important complication of liver surgery and transplantation. The mechanisms of this injury as well as the subsequent reparative and regenerative processes have been the subject of thorough study. In this paper, we discuss the complex and coordinated responses leading to parenchymal damage after liver ischemia/reperfusion as well as the manner in which the liver clears damaged cells and regenerates functional mass.http://dx.doi.org/10.6064/2012/513192
spellingShingle Alex B. Lentsch
Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion
Scientifica
title Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion
title_full Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion
title_fullStr Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion
title_full_unstemmed Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion
title_short Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion
title_sort regulatory mechanisms of injury and repair after hepatic ischemia reperfusion
url http://dx.doi.org/10.6064/2012/513192
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