Investigating the role of hyperexpressed HCN1 in inducing myocardial infarction through activation of the NF-κB signaling pathway
We investigated the protective effect of the NF-κB inhibitor, pyrrolidine dithiocarbamate (PDTC) on cardiomyocyte injury induced by HCN1 channel overexpression, and explored the underlying mechanisms. An HCN1 overexpression vector was constructed and transfected into H9C2 cells, followed by PDTC tre...
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Main Authors: | Liang Xiao, Zhang Jie, Luo Ya |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2024-12-01
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Series: | Open Life Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1515/biol-2022-0967 |
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