Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells

Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells

Abstract Non-homologous end joining (NHEJ) is the predominant pathway that repairs DNA double-stranded breaks (DSBs) in vertebrates. However, due to challenges in detecting DSBs in living cells, the repair capacity of the NHEJ pathway is unknown. The DNA termini of many DSBs must be processed to all...

Full description

Saved in:
Bibliographic Details
Main Authors: Mariia Mikhova, Noah J. Goff, Tomáš Janovič, Joshua R. Heyza, Katheryn Meek, Jens C. Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54545-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items