Comparison of urine and serum IgG detection ELISA for tegumentary leishmaniasis diagnosis and prognosis

Comparison of urine and serum IgG detection ELISA for tegumentary leishmaniasis diagnosis and prognosis

Laboratorial diagnosis of tegumentary leishmaniasis (TL) is hampered by variable sensitivity and/or specificity of the tests, which are still hampered by blood́ invasive collection. In this context, in the present study, we develop a serum- and urine-based ELISA to TL diagnoses. A recombinant protei...

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Main Authors: Raquel S.B. Câmara, Isabela A.G. Pereira, Daniela P. Lage, Danniele L. Vale, Fernanda Ludolf, Nathália C. Galvani, Camila S. Freitas, João A. Oliveira-da-Silva, Bárbara P.N. Assis, Ana T. Chaves, Mário S. Giusta, Grasiele S.V. Tavares, César N. Pereira, Alexsandro S. Galdino, Unaí Tupinambás, Miguel A. Chávez-Fumagalli, Vanessa P.M. Pascoal, Marcela T.C. Eller, Manoel O. da Costa Rocha, Myron Christodoulides, Ricardo A. Machado-de-Ávila, Denise U. Gonçalves, Eduardo A.F. Coelho
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Immunobiology
Subjects:
Tegumentary leishmaniasis
Leishmania braziliensis
Enzyme-linked immunosorbent assay
Urine
Diagnosis
Recombinant protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298524000718
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