<i>In vitro</i> and <i>in vivo</i> tropism and biodistribution of recombinant simian adenovirus type 25

<i>In vitro</i> and <i>in vivo</i> tropism and biodistribution of recombinant simian adenovirus type 25

Introduction. Recombinant adenoviruses are widely used in the development of vaccines for a variety of infectious diseases. Despite numerous clinical studies, only a few types of human (types 5 and 26) and simian (isolate Y25) adenoviruses are currently used to produce vaccine formulations. Differen...

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Main Authors: Irina V. Vavilova, Tatiana A. Ozharovskaia, Olga V. Zubkova, Olga Popova, Daria V. Voronina, Polina P. Goldovskaya, Denis I. Zrelkin, Alina Sh. Dzharullaeva, Inna V. Dolzhikova, Dmitry V. Shcheblyakov, Denis Yu. Logunov, Alexander L. Gintsburg
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2024-11-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
adenovirus vector
human adenovirus
simian adenovirus
tropism
biodistribution
acute toxicity
Online Access:https://microbiol.crie.ru/jour/article/viewFile/18681/1516
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