Repurposing Etalocib suppresses multidrug-resistant Staphylococcus aureus by disrupting the bacterial membrane

Repurposing Etalocib suppresses multidrug-resistant Staphylococcus aureus by disrupting the bacterial membrane

Abstract Background The emergence of multidrug-resistant (MDR) Staphylococcus aureus (S. aureus) seriously poses a serious threat to human health and presents a significant clinical challenge. Therefore, it is urgent to explore alternative treatments and develop novel antimicrobial agents. To invest...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xuancheng Huang, Congcong Li, Chaoqin Zhang, Yong Xiang, Zhijian Yu, Peiyu Li, Bing Bai, Zewen Wen, Tieying Hou
Format:	Article
Language:	English
Published:	BMC 2025-08-01
Series:	BMC Microbiology
Subjects:	Etalocib S. aureus Antibacterial effect Bacterial membrane
Online Access:	https://doi.org/10.1186/s12866-025-04163-5
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Repurposing AZD-5991 for inhibiting growth and biofilm formation of Staphylococcus aureus by disrupting the cell membrane and targeting FabI
by: Yuanyuan Tang, et al.
Published: (2025-07-01)

Molecular identification and resistance phenotype analysis of Staphylococcus aureus from chicken sources
by: Gang Qiu, et al.
Published: (2025-12-01)

Whole-genome sequencing and biofilm gene characterization in multidrug-Resistant Staphylococcus aureus clinical strains
by: Emira Noumi, et al.
Published: (2025-09-01)

Effects of Storage on Resistant Staphylococcus Aureus Strains
by: Ajagbe, J.M. * , Kumurya, A.S. , Rabiu, M. , Dogo, E.B., Ega, B. , Tukur, A.D. , Opalekunde, A.B. , and Yusuf, A.A.
Published: (2018-09-01)

Clinico-epidemiology and resistance patterns of community-acquired and hospital-acquired staphylococcus aureus sepsis in children
by: Sahar Siddiqui, et al.
Published: (2025-05-01)

STUDY THE PATHOLOGIC EFFECT OF Staphylococcus aureus POST INFECTION IN RABBITS
by: ZainabJamal M. Jawad, et al.
Published: (2018-11-01)

EFFECT OF IMMUNOGLOBULIN Y PURIFIED FROM IMMUNIZED HEN EGGS ON THE GROWTH OF STAPHYLOCOCCUS AUREUS
by: Ali A. Al-Edany
Published: (2011-12-01)

Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus
by: Debmita Debdas, et al.
Published: (2011-03-01)

Structural and functional analysis of the accessory gene regulators of Staphylococcus aureus and Staphylococcus epidermidis: an in Silico approach
by: Subhamoy Dey, et al.
Published: (2025-08-01)

CALCIUM AND PHOSPHORUS CONCENTRATION IN RABBITS WITH STAPHYLOCOCCUS AUREUS INFECTION
by: M. Toneva, et al.
Published: (2023-03-01)

Biofilm formation by clinically isolated Staphylococcus Aureus from India
by: Alasthimannahalli Gangadhara Triveni, et al.
Published: (2018-12-01)

Study on biofilm-forming properties of clinical isolates of Staphylococcus aureus
by: Yasmeen Taj, et al.
Published: (2011-12-01)

Why We Should Be Concerned about Methicillin-Resistant Staphylococcus aureus (MRSA)
by: Austin B. Mogen, et al.
Published: (2016-02-01)

mec A AND mec C GENES PROFILE OF CLINICAL ISOLATES OF Staphylococcus aureus
by: Zainab Dakhil Degaim, et al.
Published: (2018-11-01)

Factors Associated with Methicillin Resistant Staphylococcus aureus Carriage
by: Masood Abdulkareem Abdulrahman, et al.
Published: (2019-08-01)

Computational Perspectives on Amoxicillin and Staphylococcus Aureus in Mirror Life
by: Lorenzo Pedroni, et al.
Published: (2025-08-01)

Advances in research on small colony variants of Staphylococcus aureus
by: Zhiyi Ye, et al.
Published: (2025-09-01)

Evaluation of Geh gene expression in Staphylococcus aureus isolated from acne patients
by: mohammed hussein
Published: (2024-10-01)

Carbohydrates in action: influencing infection and amplification of Staphylococcus aureus bacteriophages
by: Poniatovskyi Vadym, et al.
Published: (2025-08-01)

Bibliometric analysis of hotspots in Staphylococcus aureus drug resistance research
by: Jianguo Shi
Published: (2025-05-01)

Identification of the Staphylococcus aureus endothelial cell surface interactome by proximity labeling
by: Marcel Rühling, et al.
Published: (2025-05-01)

Antibacterial activity of tamoxifen derivatives against methicillin-resistant Staphylococcus aureus
by: Irene Molina Panadero, et al.
Published: (2025-04-01)

Prevalence and Characterization of <i>Staphylococcus aureus</i> and Methicillin-Resistant <i>Staphylococcus aureus</i> Isolated from Guangxi Dairy Farms
by: Kai Ma, et al.
Published: (2025-06-01)

Response sensitivity to bacteriophages of Staphylococcus aureus strains isolated from the microbiota of the oropharynx in children of Irkutsk
by: E. V. Grigorova, et al.
Published: (2017-09-01)

PREVALENCIA DE Staphylococcus epidermidis Y Staphylococcus aureus EN PACIENTES CON CONJUNTIVITIS
by: P. Hernández-Rodríguez, et al.
Published: (2005-12-01)

Isolation and molecular diagnosis of Staphylococcus aureus from eye infections in domestic cats in Mosul city.
by: Nagham D. Alnajmawe, et al.
Published: (2025-01-01)

Molecular investigation of methicillin-resistant staphylococcus aureus isolates from blood: USA600 emerges as the major type
by: Mehdi Goudarzi, et al.
Published: (2018-05-01)

Features of Staphylococcus Aureus Antibiotic Sensitivity in Children with Atopic Dermatitis
by: Nikolay N. Murashkin, et al.
Published: (2023-11-01)

Antibacterial Evaluation of Tricyclic Antidepressants Against <i>S. aureus</i> and the Possible Pathways of the Mechanism of Action
by: Vitória Pessoa de Farias Cabral, et al.
Published: (2025-06-01)

Clinical and laboratory predictors of mortality in Staphylococcus aureus bacteremia
by: Deniz Borcak, et al.
Published: (2025-08-01)

Prevalência de Staphylococcus aureus resistente à oxacilina isolado em profissionais de enfermagem
by: Letícia Pimenta Lopes, et al.
Published: (2018-11-01)

Prevalence and antibiotic resistance of Staphylococcus aureus in wound infections: a hospital study in Hawassa, Ethiopia
by: Biruktawit Sahle, et al.
Published: (2024-10-01)

Prevalência de Staphylococcus aureus resistente à oxacilina isolado em profissionais de enfermagem
by: Letícia Pimenta Lopes, et al.
Published: (2018-11-01)

Molecular typing of Staphylococcus aureus collected from a Major Hospital in Amman, Jordan
by: Dana A Bazzoun, et al.
Published: (2014-04-01)

MOLECULAR DETECTION OF METHICILLIN-RESISTANT Staphylococcus aureus ISOLATED FROM MILK AND CHEESE OF COW AND BUFFALOES IN BASRAH CITY
by: Weam Abd Ali Aboud, et al.
Published: (2018-11-01)

Molecular detection of the genes encoding virulence factors of coagulase-positive Staphylococcus aureus isolated from restaurants
by: Azer S. Saber, et al.
Published: (2025-04-01)

Enhanced sensitivity and efficiency of detection of Staphylococcus aureus based on modified magnetic nanoparticles by photometric systems
by: Ebrahim Naderlou, et al.
Published: (2020-01-01)

Quaternized chitosan derivatives inhibit growth and affect biofilm formation of Staphylococcus aureus
by: Alex Miranda, et al.
Published: (2025-08-01)

In vitro biological effects of pinewood sawdust and sugarcane bagasse-derived xylooligosaccharides on Lactobacillus biomass and antibacterial properties of its postbiotics on multidrug-resistant mastitogenic Staphylococcus aureus
by: Claudious Gufe, et al.
Published: (2025-12-01)

DETECTION OF INTRACELLULAR ADHESION GENE (icaA and icaD)AND BIOFILM FORMATION STAPHYLOCOCCUS AUREUS ISOLATES FROM MASTITIS MILK OF SHEEP AND GOAT
by: Mohammed Khudor, et al.
Published: (2022-02-01)