Novel prophylactic and therapeutic multi-epitope vaccine based on Ag85A, Ag85B, ESAT-6, and CFP-10 of Mycobacterium tuberculosis using an immunoinformatics approach

Novel prophylactic and therapeutic multi-epitope vaccine based on Ag85A, Ag85B, ESAT-6, and CFP-10 of Mycobacterium tuberculosis using an immunoinformatics approach

Objectives Current tuberculosis (TB) control strategies face limitations, such as low antibiotic treatment compliance and a rise in multidrug resistance. Furthermore, the lack of a safe and effective vaccine compounds these challenges. The limited efficacy of existing vaccines against TB underscores...

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Bibliographic Details
Main Authors: Muhammad Fikri Nugraha, Daniel Alexander Changestu, Rizky Ramadhan, Tasya Salsabila, Arsila Nurizati, Sari Eka Pratiwi, Ysrafil Ysrafil
Format: Article
Language:English
Published: Korea Disease Control and Prevention Agency 2024-08-01
Series:Osong Public Health and Research Perspectives
Subjects:
multi-epitope vaccine
prophylaxis tuberculosis vaccine
therapeutic tuberculosis vaccine
Online Access:http://ophrp.org/upload/pdf/j-phrp-2024-0026.pdf
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