Pneumococcal Septic Arthritis among Adults, France, 2010–2018
Streptococcus pneumoniae infection is considered an uncommon cause of arthritis in adults. To determine the clinical and microbiological characteristics of pneumococcal septic arthritis, we retrospectively studied a large series of cases among adult patients during the 2010–2018 conjugate vaccine e...
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2025-01-01
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| Series: | Emerging Infectious Diseases |
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| Online Access: | https://wwwnc.cdc.gov/eid/article/31/1/24-0321_article |
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| author | Farida Hamdad Nadim El Bayeh Gabriel Auger Olivia Peuchant Frédéric Wallet Raymond Ruimy Florence Reibel Christian Martin Marie-Cécile Ploy Frédéric Robin Chrislène Laurens Philippe Lanotte Marie Kempf Jennifer Tetu Hélène Revillet Isabelle Patry Philippe Cailloux Mélissa Azouaou Emmanuelle Varon Pierre Duhaut Alain Lozniewski Vincent Cattoir |
| author_facet | Farida Hamdad Nadim El Bayeh Gabriel Auger Olivia Peuchant Frédéric Wallet Raymond Ruimy Florence Reibel Christian Martin Marie-Cécile Ploy Frédéric Robin Chrislène Laurens Philippe Lanotte Marie Kempf Jennifer Tetu Hélène Revillet Isabelle Patry Philippe Cailloux Mélissa Azouaou Emmanuelle Varon Pierre Duhaut Alain Lozniewski Vincent Cattoir |
| author_sort | Farida Hamdad |
| collection | DOAJ |
| description |
Streptococcus pneumoniae infection is considered an uncommon cause of arthritis in adults. To determine the clinical and microbiological characteristics of pneumococcal septic arthritis, we retrospectively studied a large series of cases among adult patients during the 2010–2018 conjugate vaccine era in France. We identified 110 patients (56 women, 54 men; mean age 65 years), and cases included 82 native joint infections and 28 prosthetic joint infections. Most commonly affected were the knee (50/110) and hip (25/110). Concomitant pneumococcal infections were found in 37.2% (38/102) and bacteremia in 57.3% (55/96) of patients, and underlying conditions were noted for 81.4% (83/102). Mortality rate was 9.4% (8/85). The proportion of strains not susceptible to penicillin was 29.1% (32/110). Of the 55 serotyped strains, 31 (56.4%) were covered by standard pneumococcal vaccines; however, several nonvaccine serotypes (mainly 23B, 24F, and 15A) had emerged, for which susceptibility to β-lactams was low.
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| format | Article |
| id | doaj-art-75a22b36c75644e1aa8576b26aef39f1 |
| institution | Kabale University |
| issn | 1080-6040 1080-6059 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj-art-75a22b36c75644e1aa8576b26aef39f12024-12-23T13:52:23ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592025-01-0131181710.3201/eid3101.240321Pneumococcal Septic Arthritis among Adults, France, 2010–2018Farida HamdadNadim El BayehGabriel AugerOlivia PeuchantFrédéric WalletRaymond RuimyFlorence ReibelChristian MartinMarie-Cécile PloyFrédéric RobinChrislène LaurensPhilippe LanotteMarie KempfJennifer TetuHélène RevilletIsabelle PatryPhilippe CaillouxMélissa AzouaouEmmanuelle VaronPierre DuhautAlain LozniewskiVincent Cattoir Streptococcus pneumoniae infection is considered an uncommon cause of arthritis in adults. To determine the clinical and microbiological characteristics of pneumococcal septic arthritis, we retrospectively studied a large series of cases among adult patients during the 2010–2018 conjugate vaccine era in France. We identified 110 patients (56 women, 54 men; mean age 65 years), and cases included 82 native joint infections and 28 prosthetic joint infections. Most commonly affected were the knee (50/110) and hip (25/110). Concomitant pneumococcal infections were found in 37.2% (38/102) and bacteremia in 57.3% (55/96) of patients, and underlying conditions were noted for 81.4% (83/102). Mortality rate was 9.4% (8/85). The proportion of strains not susceptible to penicillin was 29.1% (32/110). Of the 55 serotyped strains, 31 (56.4%) were covered by standard pneumococcal vaccines; however, several nonvaccine serotypes (mainly 23B, 24F, and 15A) had emerged, for which susceptibility to β-lactams was low. https://wwwnc.cdc.gov/eid/article/31/1/24-0321_articleStreptococcus pneumoniaejoint infectionseptic arthritisadultbacteriaFrance |
| spellingShingle | Farida Hamdad Nadim El Bayeh Gabriel Auger Olivia Peuchant Frédéric Wallet Raymond Ruimy Florence Reibel Christian Martin Marie-Cécile Ploy Frédéric Robin Chrislène Laurens Philippe Lanotte Marie Kempf Jennifer Tetu Hélène Revillet Isabelle Patry Philippe Cailloux Mélissa Azouaou Emmanuelle Varon Pierre Duhaut Alain Lozniewski Vincent Cattoir Pneumococcal Septic Arthritis among Adults, France, 2010–2018 Emerging Infectious Diseases Streptococcus pneumoniae joint infection septic arthritis adult bacteria France |
| title | Pneumococcal Septic Arthritis among Adults, France, 2010–2018 |
| title_full | Pneumococcal Septic Arthritis among Adults, France, 2010–2018 |
| title_fullStr | Pneumococcal Septic Arthritis among Adults, France, 2010–2018 |
| title_full_unstemmed | Pneumococcal Septic Arthritis among Adults, France, 2010–2018 |
| title_short | Pneumococcal Septic Arthritis among Adults, France, 2010–2018 |
| title_sort | pneumococcal septic arthritis among adults france 2010 2018 |
| topic | Streptococcus pneumoniae joint infection septic arthritis adult bacteria France |
| url | https://wwwnc.cdc.gov/eid/article/31/1/24-0321_article |
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