Etoposide targets 2A protease to inhibit enterovirus 71 replication

Etoposide targets 2A protease to inhibit enterovirus 71 replication

ABSTRACT Enterovirus 71 (EV71) is a major pathogen that causes hand, foot, and mouth disease (HFMD) in infants and children. Notably, no clinically approved drugs specifically target EV71. The EV71 2A protease (2Apro), a cysteine protease produced by the virus, is essential for the virus’ replicatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Qinqin Liang, Sai Shi, Qingjie Zhang, Yaxin Wang, Sheng Ye, Binghong Xu
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:Microbiology Spectrum
Subjects:
HFMD
EV71
antiviral
Etoposide
inhibitor
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02200-24
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items