Sclareolide as Antifungal Strategy Against <i>Cryptococcus neoformans</i>: Unveiling Its Mechanisms of Action

Sclareolide as Antifungal Strategy Against <i>Cryptococcus neoformans</i>: Unveiling Its Mechanisms of Action

Cryptococcal infection commonly begins as an opportunistic infection in humans, however, this can escalate to a systemic or life-threatening form in immunocompromised individuals. Here, we aim to identify novel antifungal molecules from plants resources. Sclareolide, a phytochemical classified as a...

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Bibliographic Details
Main Authors: Arumugam Ganeshkumar, Patricia Michelle Nagai de Lima, Jebiti Haribabu, Bruno Montanari Borges, Nycolas Willian Preite, Flavio Vieira Loures, Arunachalam Arulraj, Juliana Campos Junqueira
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Microorganisms
Subjects:
<i>Cryptococcus</i>
phytochemicals
sclareolide
antifungals
ROS and MMP
Online Access:https://www.mdpi.com/2076-2607/12/11/2324
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