The efficacy and safety of Ginkgo biloba L. leaves extract combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta-analysis of 41 randomized controlled trials

The efficacy and safety of Ginkgo biloba L. leaves extract combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta-analysis of 41 randomized controlled trials

BackgroundDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease in the world. However, the current conventional approaches have not yet achieved satisfactory efficacy. As one of the most influential products in botanical medicine, Ginkgo biloba L. leaves extract (GBE)...

Full description

Saved in:

Bibliographic Details
Main Authors:	Zehua Zhang, Shiyun Tang, Shiyu Liu, Yulin Leng, Xiaoxu Fu, Hongyan Xie, Hong Gao, Chunguang Xie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Pharmacology
Subjects:	Ginkgo biloba L. leaves extract diabetic kidney disease systematic review randomized controlled trials meta-analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1408546/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The GbbZIP41 transcription factor participates in terpene trilactones biosynthesis in Ginkgo biloba L.
by: Nuo Wang, et al.
Published: (2025-03-01)

Ultrasonic and Microwave-assisted Solid-Liquid Extraction of Ginkgo biloba Phenolics: Study about Mass Transfer and PID Control
by: Chi XU, et al.
Published: (2025-02-01)

Ginkgo biloba Bitki Ekstraktı ile Muamele Edilmiş Kayısıların Yapay Yolla Kurutulması ve Kalite Özelliklerinin Belirlenmesi
by: Ahsen Rayman Ergün, et al.
Published: (2021-03-01)

Differences in antioxidant properties of ginkgo leaves collected from male and female trees
by: Koczka Noémi, et al.
Published: (2015-03-01)

The mechanisms of efficacy and safety of Ginkgo biloba extract in acute ischemic stroke: a real-world study
by: Xiangqian Huang, et al.
Published: (2025-02-01)

Ginkgo biloba extract EGb761 mitigates ischemic stroke via metabolic pathway modulation
by: Xiaoyao Liu, et al.
Published: (2025-01-01)

Effect of in vitro gastrointestinal digestion on the chemical composition and antioxidant properties of Ginkgo biloba leaves decoction and commercial capsules
by: Zhou Yubo, et al.
Published: (2022-12-01)

Ginkgo biloba L.: An Updated Review on the Pharmacological Activities, Pharmacokinetics and Drug Interactions
by: Zahra Moeinipour, et al.
Published: (2024-12-01)

<i>Ginkgo biloba</i> Extract Prescriptions Are Associated with Slower Progression of Dementia Severity—Analysis of Longitudinal Real-World Data
by: Jens Bohlken, et al.
Published: (2024-12-01)

(<i>aS</i>)-Glucosciadopitysin, a New Biflavonoid Glycoside from the Leaves of <i>Ginkgo biloba</i> and Osteogenic Activity of Bioflavonoids
by: Se Yun Jeong, et al.
Published: (2025-01-01)

Screening of Solvent Systems for Countercurrent Chromatography Separation of Polar Constituents from <i>Ginkgo biloba</i> L. Seeds
by: Ruxi Hu, et al.
Published: (2025-01-01)

Plastome data provides new insights into population differentiation and evolution of Ginkgo in the Sichuan Basin of China
by: Liyun Nie, et al.
Published: (2025-01-01)

Extending Ginkgo to Manage Reconfigurable Hardware-Based Kernels
by: Alejandro Morales-Peña, et al.
Published: (2025-01-01)

Estimation of Individual Tree Structure and Wood Density Parameters for <i>Ginkgo biloba</i> Using Terrestrial LiDAR and Resistance Drill Data
by: Ting Li, et al.
Published: (2024-12-01)

Determining the mechanism of Shuxuening injection against liver cirrhosis through network pharmacology and animal experiments
by: Qiyao Liu, et al.
Published: (2025-01-01)

Proteomic analysis of whole blood to investigate the therapeutic effects of nervonic acid on cerebral ischemia-reperfusion injury in rats
by: Qingqing Li, et al.
Published: (2025-01-01)

MicroRNA Expression Profile in CAD Patients and the Impact of ACEI/ARB
by: Martina Weber, et al.
Published: (2011-01-01)

Efficacy and safety of tripterygium glycosides combined with ACEI/ARB on diabetic nephropathy: a meta-analysis
by: Zhuan’E. Yao, et al.
Published: (2025-01-01)

Evaluation of Antioxidant Activities and Tyrosinase Inhibitory Effects of Ginkgo biloba Tea Extract
by: Pongsathorn Klomsakul, et al.
Published: (2022-01-01)

The Ginkgo biloba Extract Reverses the Renal Effects of Titanium Dioxide Nanoparticles in Adult Male Rats
by: Carlos Enrique Escárcega-González, et al.
Published: (2016-01-01)

The efficacy and safety of qiwei baizhu san in the treatment of type 2 diabetes mellitus: a systematic review and meta-analysis
by: Quan Zhang, et al.
Published: (2025-01-01)

Variation in Flavonoid Composition and Radical-Scavenging Activity in Ginkgo biloba L. due to the Growth Location and Time of Harvest
by: Laura Rimkiene, et al.
Published: (2017-01-01)

Ginkgo biloba Extract Improves Insulin Signaling and Attenuates Inflammation in Retroperitoneal Adipose Tissue Depot of Obese Rats
by: Bruna Kelly Sousa Hirata, et al.
Published: (2015-01-01)

The sensitivity of reconstructed carbon dioxide concentrations to stomatal preparation methods using a leaf gas exchange model
by: Michael D. Machesky, et al.
Published: (2025-01-01)

Effects of Ginkgo biloba Extract on Inflammatory Mediators (SOD, MDA, TNF-α, NF-κBp65, IL-6) in TNBS-Induced Colitis in Rats
by: Yan-Hong Zhou, et al.
Published: (2006-01-01)

Biochemical Constituent of Ginkgo biloba (Seed) 80% Methanol Extract Inhibits Cholinesterase Enzymes in Javanese Medaka (Oryzias javanicus) Model
by: Ibrahim Hassan, et al.
Published: (2020-01-01)

Advanced Amperometric Microsensors for the Electrochemical Quantification of Quercetin in <i>Ginkgo biloba</i> Essential Oil from Regenerative Farming Practices
by: Elena Oancea, et al.
Published: (2024-12-01)

Synthesis of silver leaves and their potential application for analysis and degradation of phenolic pollutants
by: Jianan Sun, et al.
Published: (2022-05-01)

Efficacy of ARB/HCTZ Combination Therapy in Uncontrolled Hypertensive Patients Compared with ARB Monotherapy: A Meta-Analysis
by: Linlin Ma, et al.
Published: (2021-01-01)

Inhibition of high glucose-induced cardiac fibroblast activation: an effective treatment for diabetic cardiomyopathy using Chinese herbal medicine
by: Bin Wan, et al.
Published: (2025-01-01)

Challenges in exercising the right to annual leave for workers on long-term sick leave in the Republic of Croatia
by: Bjelić-Gaćeša Dragana
Published: (2024-01-01)

NOD1: a metabolic modulator
by: Ruobing Tang, et al.
Published: (2025-01-01)

Impacts of extraction solvents and processing techniques on phytochemical composition and antioxidant property of mulberry (Morus spp.) leaves
by: Chiu-Hsun Liao, et al.
Published: (2025-12-01)

A comprehensive dataset of tomato leaf images for disease analysis in BangladeshMendeley Data
by: Mangsura Kabir Oni, et al.
Published: (2025-04-01)

N-Terminal Region of GbIspH1, Ginkgo biloba IspH Type 1, May Be Involved in the pH-Dependent Regulation of Enzyme Activity
by: Bok-Kyu Shin, et al.
Published: (2015-01-01)

Flavonoid Compounds from Ethanol Extract of Sungkai Leaves (Peronema canescens. Jack) and Antibacterial Activity Test Against Staphylococcus epidermidis and Escherchia coli
by: Nindita Clourisa Amaris Susanto, et al.
Published: (2022-12-01)

Impact of the unconventional extraction on antioxidants and antimicrobial characteristics of hibiscus and olive leaves extracts
by: Abdel-Aziz R.E. El-Hadary, et al.
Published: (2025-01-01)

Isolation of Bioactive Compound in Methanolic Extract of Putat Leaves (Planchonia valida) as Antioxidant
by: Faizar Farid, et al.
Published: (2022-12-01)

Effectiveness of Complementary Therapy Decoction of Celery Leaves and Bay Leaves on Reducing Hypertension in Paku Alam Village
by: Trisna Devina, et al.
Published: (2025-01-01)

POTENTIALLY OF PURPLE LEAVES TO INCREASE OSTEOBLASTAT ALVEOLAR BONE RAT INDUCED PORPHYROMONAS GINGIVALIS
by: Pramita Wahyu Dyasti, et al.
Published: (2021-03-01)