A subpopulation of projections from the parabrachial nucleus to the central amygdala mediates itch

A subpopulation of projections from the parabrachial nucleus to the central amygdala mediates itch

Abstract The parabrachial nucleus (PBN) plays a crucial role in transmitting itch and affective pain signals to the brain regions such as the central amygdala (CeA). While CGRP+ PBN neurons have been implicated in itch processing, the specific projections involved remain unclear. This study aimed to...

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Bibliographic Details
Main Authors: Darya Pavlenko, Hirotake Ishida, Anika Markan, Tasuku Akiyama
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Pruritus
Optogenetics
Scratching
CGRP
Pain
Online Access:https://doi.org/10.1038/s41598-025-08612-z
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