A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis
Protein-losing enteropathy (PLE) can be caused by erosive and nonerosive gastrointestinal diseases, mesenteric lymphatic obstruction, and increased central venous pressure. Superior mesenteric artery pathology (SMAP), including dissection or occlusion is another very rarely reported etiology. Manage...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Journal of Vascular Surgery Cases and Innovative Techniques |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468428724002077 |
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| author | Nedaa Skeik, MD, FACC, FACP, FSVM, RPVI Rebecca Windschitl, MD Naureen Qadri, MD Jesse Manunga, MD |
| author_facet | Nedaa Skeik, MD, FACC, FACP, FSVM, RPVI Rebecca Windschitl, MD Naureen Qadri, MD Jesse Manunga, MD |
| author_sort | Nedaa Skeik, MD, FACC, FACP, FSVM, RPVI |
| collection | DOAJ |
| description | Protein-losing enteropathy (PLE) can be caused by erosive and nonerosive gastrointestinal diseases, mesenteric lymphatic obstruction, and increased central venous pressure. Superior mesenteric artery pathology (SMAP), including dissection or occlusion is another very rarely reported etiology. Management of PLE includes treatment of the underlying cause in addition to a low-fat, high-protein, medium-chain triglyceride diet to improve nutrition. The management of SMAP and its complications, including PLE, necessitates a multidisciplinary approach involving vascular surgeons and gastroenterologists. Treatment options include conservative measures, medical management, and, in some cases, revascularization. We report a unique case of SMAP-induced PLE leading to a fatal outcome. We further conducted a literature review with the aim of summarizing the existing literature on this topic and providing intrigued readers with the most relevant and up-to-date information on this topic in hopes of improving the care of patients presenting with this unique entity. To our knowledge, our patient represents the only case in the literature where segmental arterial mediolysis is the underlying cause of superior mesenteric artery dissection and occlusion leading to PLE. |
| format | Article |
| id | doaj-art-747a2c9ec7fc40d9a05aa98d48f91f1b |
| institution | Kabale University |
| issn | 2468-4287 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Vascular Surgery Cases and Innovative Techniques |
| spelling | doaj-art-747a2c9ec7fc40d9a05aa98d48f91f1b2024-11-30T07:13:34ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872024-12-01106101623A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysisNedaa Skeik, MD, FACC, FACP, FSVM, RPVI0Rebecca Windschitl, MD1Naureen Qadri, MD2Jesse Manunga, MD3Department of Vascular Medicine, Thrombophilia and Anticoagulation Clinic, Vein Center, Abbott Northwestern Hospital/Minneapolis Heart Institute, Minneapolis, MN; Correspondence: Nedaa Skeik, MD, FACC, FACP, FSVM, RPVI, Professor of Medicine, Section Head, Vascular Medicine, Medical Director, Thrombophilia and Anticoagulation Clinic, Medical Director, Vein Center, Abbott Northwestern Hospital/Minneapolis Heart Institute, 920 East 28th St, Minneapolis, MN 5540Internal medicine, Abbott Northwestern Hospital, Minneapolis, MNInternal medicine, Abbott Northwestern Hospital, Minneapolis, MNDepartment of Vascular Surgery, Abbott Northwestern Hospital/Minneapolis Heart Institute, Minneapolis, MNProtein-losing enteropathy (PLE) can be caused by erosive and nonerosive gastrointestinal diseases, mesenteric lymphatic obstruction, and increased central venous pressure. Superior mesenteric artery pathology (SMAP), including dissection or occlusion is another very rarely reported etiology. Management of PLE includes treatment of the underlying cause in addition to a low-fat, high-protein, medium-chain triglyceride diet to improve nutrition. The management of SMAP and its complications, including PLE, necessitates a multidisciplinary approach involving vascular surgeons and gastroenterologists. Treatment options include conservative measures, medical management, and, in some cases, revascularization. We report a unique case of SMAP-induced PLE leading to a fatal outcome. We further conducted a literature review with the aim of summarizing the existing literature on this topic and providing intrigued readers with the most relevant and up-to-date information on this topic in hopes of improving the care of patients presenting with this unique entity. To our knowledge, our patient represents the only case in the literature where segmental arterial mediolysis is the underlying cause of superior mesenteric artery dissection and occlusion leading to PLE.http://www.sciencedirect.com/science/article/pii/S2468428724002077Superior mesenteric vasculopathySegmental arterial mediolysisProtein-losing enteropathy |
| spellingShingle | Nedaa Skeik, MD, FACC, FACP, FSVM, RPVI Rebecca Windschitl, MD Naureen Qadri, MD Jesse Manunga, MD A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis Journal of Vascular Surgery Cases and Innovative Techniques Superior mesenteric vasculopathy Segmental arterial mediolysis Protein-losing enteropathy |
| title | A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis |
| title_full | A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis |
| title_fullStr | A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis |
| title_full_unstemmed | A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis |
| title_short | A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis |
| title_sort | unique case of protein losing enteropathy as a complication of segmental arterial mediolysis |
| topic | Superior mesenteric vasculopathy Segmental arterial mediolysis Protein-losing enteropathy |
| url | http://www.sciencedirect.com/science/article/pii/S2468428724002077 |
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