PPAR-γ抑制剂T0070907对人鼻咽癌细胞的生长抑制作用
【目的】 探讨PPAR-γ选择性抑制剂T0070907影响鼻咽癌(NPC)细胞体外生长的作用机制65377;【方法】 通过RT-PCR和Western blotting检测PPAR-γ受体在5株NPC细胞株(CNE165380;CNE265380;HONE165380;SUNE1和5-8F)中mRNA和蛋白水平的表达;MTT法检测T0070907对NPC细胞生长情况的影响;流式细胞术和Western blotting检测T0070907对NPC细胞的细胞周期和细胞周期相关蛋白表达的影响65377;【结果】 PPAR-γ在5株NPC细胞中均有表达;T0070907对NPC细胞株有明显生长抑制作用...
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Format: | Article |
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Language: | zho |
Published: |
Editorial Office of Journal of Sun Yat-sen University
2010-01-01
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Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
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Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43577512/ |
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