DNA 5mC methylation inhibits the formation of G-quadruplex structures in the genome
Abstract Background G-quadruplex structures (G4s) have been identified in the genomes of many organisms and have been proven to play significant epigenetic regulatory roles in gene transcription. Intriguingly, only a small portion of the predicted G4-forming sequences can fold into G4s under cellula...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Genome Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13059-025-03678-4 |
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