An example of cytisine overdose with no consequent side-effects: a case report
Abstract Background Cytisine is an alkaloid that is molecularly similar to nicotine and it is commonly used to treat smoking cessation. While it is considered a reasonably safe treatment option, cytisine intoxication in humans exhibits several adverse effects. These involve the gastrointestinal syst...
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| Format: | Article |
| Language: | English |
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BMC
2024-11-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | https://doi.org/10.1186/s13256-024-04938-w |
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| author | Simone Campagnari Lorenzo Zamboni Isabella Barbon Francesca Fusina Fabio Lugoboni |
| author_facet | Simone Campagnari Lorenzo Zamboni Isabella Barbon Francesca Fusina Fabio Lugoboni |
| author_sort | Simone Campagnari |
| collection | DOAJ |
| description | Abstract Background Cytisine is an alkaloid that is molecularly similar to nicotine and it is commonly used to treat smoking cessation. While it is considered a reasonably safe treatment option, cytisine intoxication in humans exhibits several adverse effects. These involve the gastrointestinal system (nausea, vomiting, diarrhea), the central nervous system (drowsiness, fatigue, delirium), and the motor system (muscle twitching and fasciculation, difficulties in walking). Case presentation We present a unique case report in which a Caucasian patient (an Italian 64-year-old woman) who was undergoing smoking cessation treatment with cytisine, and due to her misunderstanding of the therapeutic indications provided, took twice the recommended dose every day for 8 days, leading to an intake of 54 mg/dl of cytisine for 3 consecutive days. Notwithstanding the high dosage, the patient did not report any adverse reactions. Conclusion This confirms the safety of the drug, even at high doses, in patients aiming to quit smoking. |
| format | Article |
| id | doaj-art-73f82615c5bb4faeaa287122584f31dc |
| institution | Kabale University |
| issn | 1752-1947 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj-art-73f82615c5bb4faeaa287122584f31dc2024-12-01T12:27:40ZengBMCJournal of Medical Case Reports1752-19472024-11-011811410.1186/s13256-024-04938-wAn example of cytisine overdose with no consequent side-effects: a case reportSimone Campagnari0Lorenzo Zamboni1Isabella Barbon2Francesca Fusina3Fabio Lugoboni4Department of Internal Medicine, Addiction Unit, Verona University HospitalDepartment of Internal Medicine, Addiction Unit, Verona University HospitalDepartment of Internal Medicine, Addiction Unit, Verona University HospitalDepartment of General Psychology, University of PadovaDepartment of Internal Medicine, Addiction Unit, Verona University HospitalAbstract Background Cytisine is an alkaloid that is molecularly similar to nicotine and it is commonly used to treat smoking cessation. While it is considered a reasonably safe treatment option, cytisine intoxication in humans exhibits several adverse effects. These involve the gastrointestinal system (nausea, vomiting, diarrhea), the central nervous system (drowsiness, fatigue, delirium), and the motor system (muscle twitching and fasciculation, difficulties in walking). Case presentation We present a unique case report in which a Caucasian patient (an Italian 64-year-old woman) who was undergoing smoking cessation treatment with cytisine, and due to her misunderstanding of the therapeutic indications provided, took twice the recommended dose every day for 8 days, leading to an intake of 54 mg/dl of cytisine for 3 consecutive days. Notwithstanding the high dosage, the patient did not report any adverse reactions. Conclusion This confirms the safety of the drug, even at high doses, in patients aiming to quit smoking.https://doi.org/10.1186/s13256-024-04938-wCytisineTobaccoOverdoseSmoking cessationNicotine |
| spellingShingle | Simone Campagnari Lorenzo Zamboni Isabella Barbon Francesca Fusina Fabio Lugoboni An example of cytisine overdose with no consequent side-effects: a case report Journal of Medical Case Reports Cytisine Tobacco Overdose Smoking cessation Nicotine |
| title | An example of cytisine overdose with no consequent side-effects: a case report |
| title_full | An example of cytisine overdose with no consequent side-effects: a case report |
| title_fullStr | An example of cytisine overdose with no consequent side-effects: a case report |
| title_full_unstemmed | An example of cytisine overdose with no consequent side-effects: a case report |
| title_short | An example of cytisine overdose with no consequent side-effects: a case report |
| title_sort | example of cytisine overdose with no consequent side effects a case report |
| topic | Cytisine Tobacco Overdose Smoking cessation Nicotine |
| url | https://doi.org/10.1186/s13256-024-04938-w |
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