Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure

Although pharmacological rhythm control of AF in patients with heart failure with reduced ejection fraction (HFrEF) does not seem to provide any benefit over rate control, catheter ablation of AF has been shown to improve clinical outcomes. These results can be explained with higher success rates of...

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Main Authors: Michela Faggioni, Domenico G Della Rocca, Sanghamitra Mohanty, Chintan Trivedi, Ugur Canpolat, Carola Gianni, Amin Al-Ahmad, Rodney Horton, Gerald Joseph Gallinghouse, John David Burkhardt, Andrea Natale
Format: Article
Language:English
Published: Radcliffe Medical Media 2020-04-01
Series:Cardiac Failure Review
Online Access:https://www.cfrjournal.com/articleindex/cfr.2019.03
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author Michela Faggioni
Domenico G Della Rocca
Sanghamitra Mohanty
Chintan Trivedi
Ugur Canpolat
Carola Gianni
Amin Al-Ahmad
Rodney Horton
Gerald Joseph Gallinghouse
John David Burkhardt
Andrea Natale
author_facet Michela Faggioni
Domenico G Della Rocca
Sanghamitra Mohanty
Chintan Trivedi
Ugur Canpolat
Carola Gianni
Amin Al-Ahmad
Rodney Horton
Gerald Joseph Gallinghouse
John David Burkhardt
Andrea Natale
author_sort Michela Faggioni
collection DOAJ
description Although pharmacological rhythm control of AF in patients with heart failure with reduced ejection fraction (HFrEF) does not seem to provide any benefit over rate control, catheter ablation of AF has been shown to improve clinical outcomes. These results can be explained with higher success rates of catheter ablation in restoring and maintaining sinus rhythm compared with antiarrhythmic drugs. In addition, pharmacotherapy is not void of side-effects, which are thought to offset its potential antiarrhythmic benefits. Therefore, efforts should be made towards optimisation of ablation techniques for AF in patients with HFrEF.
format Article
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institution Kabale University
issn 2057-7540
2057-7559
language English
publishDate 2020-04-01
publisher Radcliffe Medical Media
record_format Article
series Cardiac Failure Review
spelling doaj-art-73f3cc84ba8846c28d4ddc4c269368622024-12-14T16:01:52ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592020-04-01610.15420/cfr.2019.03Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart FailureMichela Faggioni0Domenico G Della Rocca1Sanghamitra Mohanty2Chintan Trivedi3Ugur Canpolat4Carola Gianni5Amin Al-Ahmad6Rodney Horton7Gerald Joseph Gallinghouse8John David Burkhardt9Andrea Natale10Department of Medicine, James J Peters Veterans Affairs Medical Center, New York, NY, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US; Department of Cardiology, Faculty of Medicine, Hacettepe University, Ankara, TurkeyTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, USTexas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US; Interventional Electrophysiology, Scripps Clinic, La Jolla, CA, US; Department of Cardiology, MetroHealth Medical Center, School of Medicine, Case Western Reserve University, Cleveland, OH, US; Division of Cardiology, Stanford University, Stanford, CA, US; Atrial Fibrillation and Arrhythmia Center, California Pacific Medical Center, San Francisco, CA, USAlthough pharmacological rhythm control of AF in patients with heart failure with reduced ejection fraction (HFrEF) does not seem to provide any benefit over rate control, catheter ablation of AF has been shown to improve clinical outcomes. These results can be explained with higher success rates of catheter ablation in restoring and maintaining sinus rhythm compared with antiarrhythmic drugs. In addition, pharmacotherapy is not void of side-effects, which are thought to offset its potential antiarrhythmic benefits. Therefore, efforts should be made towards optimisation of ablation techniques for AF in patients with HFrEF.https://www.cfrjournal.com/articleindex/cfr.2019.03
spellingShingle Michela Faggioni
Domenico G Della Rocca
Sanghamitra Mohanty
Chintan Trivedi
Ugur Canpolat
Carola Gianni
Amin Al-Ahmad
Rodney Horton
Gerald Joseph Gallinghouse
John David Burkhardt
Andrea Natale
Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure
Cardiac Failure Review
title Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure
title_full Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure
title_fullStr Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure
title_full_unstemmed Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure
title_short Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure
title_sort long term outcome of pulmonary vein isolation versus amiodarone therapy in patients with coexistent persistent af and congestive heart failure
url https://www.cfrjournal.com/articleindex/cfr.2019.03
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