Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis

Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis

IntroductionSepsis-induced cardiomyopathy is a common complication of sepsis and is associated with higher mortality. To date, effective diagnostic and management strategies are still lacking. Recent studies suggest that ferroptosis plays a critical role in sepsis-induced cardiomyopathy and ferropto...

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Main Authors: Jialin Li, Fang Xiao, Bingsen Lin, Zhilei Huang, Mingyue Wu, Huan Ma, Ruoxu Dou, Xiaodong Song, Zhongxing Wang, Changjie Cai, Xiangdong Guan, Jie Xu, Fu-Li Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
sepsis-induced cardiomyopathy
ferrostatin-1(Fer-1)
neutrophil
chemokine
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1510232/full
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