Risk factors for COVID-19-associated mucormycosis (CAM): A case-control study
Introduction: Mucormycosis, a rare but serious fungal infection, surged during the second wave of the COVID-19 pandemic. Despite various proposed causative factors, published data are limited. This study aimed to identify risk factors for COVID-19-associated mucormycosis. Methods: A case-control stu...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-07-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_1984_24 |
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| Summary: | Introduction:
Mucormycosis, a rare but serious fungal infection, surged during the second wave of the COVID-19 pandemic. Despite various proposed causative factors, published data are limited. This study aimed to identify risk factors for COVID-19-associated mucormycosis.
Methods:
A case-control study was conducted in the Nagpur district. Cases were recruited from suspected or confirmed mucormycosis cases reported to district health authorities. Controls were household members who had COVID-19 but did not develop mucormycosis. Predisposing and treatment-related factors were analyzed.
Results:
Analysis revealed significant associations between mucormycosis and diabetes mellitus (OR-10.8; CI-1.1–103.6) and corticosteroid use (OR-97.6; CI-3.2–2927.1). Factors such as humidifier use and mask usage did not show a significant association.
Conclusion:
Optimal use of oxygen and corticosteroids is crucial, particularly in diabetic COVID-19 patients, to prevent mucormycosis. |
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| ISSN: | 2249-4863 2278-7135 |