Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study

Introduction Fear of recurrence is a transdiagnostic problem experienced by people with psychosis, which is associated with anxiety, depression and risk of future relapse events. Despite this, there is a lack of available psychological interventions for fear of recurrence, and psychological therapie...

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Main Authors: Sharon Anne Simpson, Gareth Jones, Jonathan Evans, Mark McCann, Marta Correia, David Thomson, Fiona Sinclair, Andrew Gumley, George Brown, Katie Robb, Stephanie Allan, Ioanna Fragkandrea-Nixon, Alie Phiri, Francis Yanga
Format: Article
Language:English
Published: BMJ Publishing Group 2024-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/12/e090566.full
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author Sharon Anne Simpson
Gareth Jones
Jonathan Evans
Mark McCann
Marta Correia
David Thomson
Fiona Sinclair
Andrew Gumley
George Brown
Katie Robb
Stephanie Allan
Ioanna Fragkandrea-Nixon
Alie Phiri
Francis Yanga
author_facet Sharon Anne Simpson
Gareth Jones
Jonathan Evans
Mark McCann
Marta Correia
David Thomson
Fiona Sinclair
Andrew Gumley
George Brown
Katie Robb
Stephanie Allan
Ioanna Fragkandrea-Nixon
Alie Phiri
Francis Yanga
author_sort Sharon Anne Simpson
collection DOAJ
description Introduction Fear of recurrence is a transdiagnostic problem experienced by people with psychosis, which is associated with anxiety, depression and risk of future relapse events. Despite this, there is a lack of available psychological interventions for fear of recurrence, and psychological therapies for schizophrenia are often poorly implemented in general. However, low-intensity psychological therapy is available for people who experience fear of recurrence in the context of cancer, which means there is an opportunity to learn what has worked in a well-implemented psychological therapy to see if any learning can be adapted for schizophrenia care. This article describes the design, methods and expected data collection of development, acceptability, feasibility, and preliminary outcome signals for a coproduced low-intensity psychological intervention targeting fear of relapse in people with schizophrenia (INDIGO), which aims to develop an acceptable psychological intervention for fear of recurrence.Methods and analysis INDIGO will use a mixed-methods approach to co-design and deliver a model and treatment pathway for a psychological intervention for people diagnosed with schizophrenia who experience fear of recurrence. The study will consist of four stages. First, in-depth interviews with mental health staff and people diagnosed with schizophrenia (with a further social network mapping task for patient participants only) to develop the intervention. Second, in-depth interviews with people who have accessed the Glasgow Fear of Recurrence service and oncology staff will be conducted to inform further development of the intervention. Third, co-design workshops will be held with people diagnosed with schizophrenia and mental health staff to co-design intervention content and the treatment pathway. Finally, people diagnosed with schizophrenia will be presented with an intervention prototype and invited to complete ‘think-aloud’ interviews to gather further feedback so adaptations can be implemented.Ethics and dissemination The INDIGO study received ethical approval from East Midlands—Nottingham 2 Research Ethics Committee (24/EM/0124). The study received independent peer review prior to funding. This co-design study is expected to lead to a future feasibility study and, if indicated, a randomised controlled trial.
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spelling doaj-art-73b3ff690e6d4c35b8c69fb776f1ceec2024-12-29T03:45:09ZengBMJ Publishing GroupBMJ Open2044-60552024-12-01141210.1136/bmjopen-2024-090566Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility studySharon Anne Simpson0Gareth Jones1Jonathan Evans2Mark McCann3Marta Correia4David Thomson5Fiona Sinclair6Andrew Gumley7George Brown8Katie Robb9Stephanie Allan10Ioanna Fragkandrea-Nixon11Alie Phiri12Francis Yanga13School of Health & Wellbeing, University of Glasgow, Glasgow, UKUniversity of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKUniversity of Glasgow, Glasgow, UKBeatson Cancer Charity, Glasgow, UKUniversity of Glasgow, Glasgow, UKNHS Greater Glasgow and Clyde, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKUniversity of Glasgow, Glasgow, UKUniversity of Glasgow, Glasgow, UKUniversity of Glasgow, Glasgow, UKBeatson West of Scotland Cancer Centre, Glasgow, UKUniversity of Glasgow, Glasgow, UKUniversity of Glasgow, Glasgow, UKIntroduction Fear of recurrence is a transdiagnostic problem experienced by people with psychosis, which is associated with anxiety, depression and risk of future relapse events. Despite this, there is a lack of available psychological interventions for fear of recurrence, and psychological therapies for schizophrenia are often poorly implemented in general. However, low-intensity psychological therapy is available for people who experience fear of recurrence in the context of cancer, which means there is an opportunity to learn what has worked in a well-implemented psychological therapy to see if any learning can be adapted for schizophrenia care. This article describes the design, methods and expected data collection of development, acceptability, feasibility, and preliminary outcome signals for a coproduced low-intensity psychological intervention targeting fear of relapse in people with schizophrenia (INDIGO), which aims to develop an acceptable psychological intervention for fear of recurrence.Methods and analysis INDIGO will use a mixed-methods approach to co-design and deliver a model and treatment pathway for a psychological intervention for people diagnosed with schizophrenia who experience fear of recurrence. The study will consist of four stages. First, in-depth interviews with mental health staff and people diagnosed with schizophrenia (with a further social network mapping task for patient participants only) to develop the intervention. Second, in-depth interviews with people who have accessed the Glasgow Fear of Recurrence service and oncology staff will be conducted to inform further development of the intervention. Third, co-design workshops will be held with people diagnosed with schizophrenia and mental health staff to co-design intervention content and the treatment pathway. Finally, people diagnosed with schizophrenia will be presented with an intervention prototype and invited to complete ‘think-aloud’ interviews to gather further feedback so adaptations can be implemented.Ethics and dissemination The INDIGO study received ethical approval from East Midlands—Nottingham 2 Research Ethics Committee (24/EM/0124). The study received independent peer review prior to funding. This co-design study is expected to lead to a future feasibility study and, if indicated, a randomised controlled trial.https://bmjopen.bmj.com/content/14/12/e090566.full
spellingShingle Sharon Anne Simpson
Gareth Jones
Jonathan Evans
Mark McCann
Marta Correia
David Thomson
Fiona Sinclair
Andrew Gumley
George Brown
Katie Robb
Stephanie Allan
Ioanna Fragkandrea-Nixon
Alie Phiri
Francis Yanga
Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study
BMJ Open
title Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study
title_full Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study
title_fullStr Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study
title_full_unstemmed Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study
title_short Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study
title_sort co designing a low intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology protocol for intervention development for future testing in a feasibility study
url https://bmjopen.bmj.com/content/14/12/e090566.full
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