Integration of single-cell and bulk analysis reveals TBXAS1 as a key platelet-related gene causing poor prognosis in osteosarcoma

Integration of single-cell and bulk analysis reveals TBXAS1 as a key platelet-related gene causing poor prognosis in osteosarcoma

BackgroundPlatelets are associated with poor prognosis in most tumors, but their specific pathogenic mechanism in osteosarcoma is not yet clear. The objective of this study is to conduct an in-depth analysis of how genes closely related to platelet function impact the prognosis of osteosarcoma patie...

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Bibliographic Details
Main Authors: Han Liu, Wacili Da, Jianhua Mu, Xuanhong He, Zhuangzhuang Li, Taojun Gong, Jingjing Wang, Li Min, Minxun Lu, Chongqi Tu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Genetics
Subjects:
osteosarcoma
blood platelets
single cell
macrophages
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1519529/full
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https://www.frontiersin.org/articles/10.3389/fgene.2024.1519529/full

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