The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical Trials

Beta-alanine is an important oral supplement for improving athletes’ performance, followed by probable effects on body composition. Current meta-analysis was performed to investigate the role of beta-alanine supplementation on body weight, fat mass, free fat mass, and body fat percentage in adults....

Full description

Saved in:
Bibliographic Details
Main Authors: Masoud Khorshidi, Sanaz Jamshidi, Javad Heshmati, Zohreh Sajadi Hezaveh, Beheshteh Olang, Omid Moradi Moghaddam, Zahra Shahveghar, Zohreh Ghoreishi, Alireza Ostadrahimi, Meysam Zarezadeh
Format: Article
Language:English
Published: Shahid Sadoughi University of Medical Sciences and Health Services 2024-11-01
Series:Journal of Nutrition and Food Security
Subjects:
Online Access:http://jnfs.ssu.ac.ir/article-1-831-en.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846172817657167872
author Masoud Khorshidi
Sanaz Jamshidi
Javad Heshmati
Zohreh Sajadi Hezaveh
Beheshteh Olang
Omid Moradi Moghaddam
Zahra Shahveghar
Zohreh Ghoreishi
Alireza Ostadrahimi
Meysam Zarezadeh
author_facet Masoud Khorshidi
Sanaz Jamshidi
Javad Heshmati
Zohreh Sajadi Hezaveh
Beheshteh Olang
Omid Moradi Moghaddam
Zahra Shahveghar
Zohreh Ghoreishi
Alireza Ostadrahimi
Meysam Zarezadeh
author_sort Masoud Khorshidi
collection DOAJ
description Beta-alanine is an important oral supplement for improving athletes’ performance, followed by probable effects on body composition. Current meta-analysis was performed to investigate the role of beta-alanine supplementation on body weight, fat mass, free fat mass, and body fat percentage in adults. Methods: Web of Science, PubMed, Scopus, Cochrane library databases, and EMBASE were searched between January 1990 and May 2021. Randomized controlled trials (RCTs) comparing beta-alanine supplementation with a placebo assessing anthropometric indices were included. Meta‐analysis was performed using the random‐effects model. Publication bias was evaluated using standard methods, and subgroup analysis and meta‐regression were carried out. Results: A total of 875 articles were identified through database searching, of which 12 RCTs with 15 datasets were included in the study. This study showed that beta-alanine supplementation did not have any significant effect on body weight [SMD, 0.08; 95% CI (−0.17, 0.33); P=0.517], fat percentage [SMD, 0.09; 95% CI (−0.18, 0.37); P=0.504], fat mass [SMD, 0.10; 95% CI (−0.29, 0.50); P=0.612], and fat free mass [SMD, 0.16; 95% CI (−0.18, 0.49); P=0.517]. Conclusions: Results showed that beta-alanine supplementation does not change body composition significantly.
format Article
id doaj-art-732c64d4a52348728a4ff1ffa268c04e
institution Kabale University
issn 2476-7417
2476-7425
language English
publishDate 2024-11-01
publisher Shahid Sadoughi University of Medical Sciences and Health Services
record_format Article
series Journal of Nutrition and Food Security
spelling doaj-art-732c64d4a52348728a4ff1ffa268c04e2024-11-09T05:28:55ZengShahid Sadoughi University of Medical Sciences and Health ServicesJournal of Nutrition and Food Security2476-74172476-74252024-11-0194788801The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical TrialsMasoud Khorshidi0Sanaz Jamshidi1Javad Heshmati2Zohreh Sajadi Hezaveh3Beheshteh Olang4Omid Moradi Moghaddam5Zahra Shahveghar6Zohreh Ghoreishi7Alireza Ostadrahimi8Meysam Zarezadeh9 Pediatric Gastroenterology, Hepatology and Nutrition Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Department of Nutritional Science, School of Nutritional Science and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran Department of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia Pediatric Gastroenterology, Hepatology and Nutrition Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Critical Care Medicine Department, Iran University of Medical Sciences, Tehran, Iran Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran Beta-alanine is an important oral supplement for improving athletes’ performance, followed by probable effects on body composition. Current meta-analysis was performed to investigate the role of beta-alanine supplementation on body weight, fat mass, free fat mass, and body fat percentage in adults. Methods: Web of Science, PubMed, Scopus, Cochrane library databases, and EMBASE were searched between January 1990 and May 2021. Randomized controlled trials (RCTs) comparing beta-alanine supplementation with a placebo assessing anthropometric indices were included. Meta‐analysis was performed using the random‐effects model. Publication bias was evaluated using standard methods, and subgroup analysis and meta‐regression were carried out. Results: A total of 875 articles were identified through database searching, of which 12 RCTs with 15 datasets were included in the study. This study showed that beta-alanine supplementation did not have any significant effect on body weight [SMD, 0.08; 95% CI (−0.17, 0.33); P=0.517], fat percentage [SMD, 0.09; 95% CI (−0.18, 0.37); P=0.504], fat mass [SMD, 0.10; 95% CI (−0.29, 0.50); P=0.612], and fat free mass [SMD, 0.16; 95% CI (−0.18, 0.49); P=0.517]. Conclusions: Results showed that beta-alanine supplementation does not change body composition significantly.http://jnfs.ssu.ac.ir/article-1-831-en.pdfbeta alanineweightobesitybody compositionmeta-analysis
spellingShingle Masoud Khorshidi
Sanaz Jamshidi
Javad Heshmati
Zohreh Sajadi Hezaveh
Beheshteh Olang
Omid Moradi Moghaddam
Zahra Shahveghar
Zohreh Ghoreishi
Alireza Ostadrahimi
Meysam Zarezadeh
The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical Trials
Journal of Nutrition and Food Security
beta alanine
weight
obesity
body composition
meta-analysis
title The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical Trials
title_full The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical Trials
title_fullStr The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical Trials
title_full_unstemmed The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical Trials
title_short The Effects of Beta-Alanine Supplementation on Body Composition Indices: A Systematic Review and Meta-Analysis of Controlled Clinical Trials
title_sort effects of beta alanine supplementation on body composition indices a systematic review and meta analysis of controlled clinical trials
topic beta alanine
weight
obesity
body composition
meta-analysis
url http://jnfs.ssu.ac.ir/article-1-831-en.pdf
work_keys_str_mv AT masoudkhorshidi theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT sanazjamshidi theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT javadheshmati theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT zohrehsajadihezaveh theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT beheshteholang theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT omidmoradimoghaddam theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT zahrashahveghar theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT zohrehghoreishi theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT alirezaostadrahimi theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT meysamzarezadeh theeffectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT masoudkhorshidi effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT sanazjamshidi effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT javadheshmati effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT zohrehsajadihezaveh effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT beheshteholang effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT omidmoradimoghaddam effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT zahrashahveghar effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT zohrehghoreishi effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT alirezaostadrahimi effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials
AT meysamzarezadeh effectsofbetaalaninesupplementationonbodycompositionindicesasystematicreviewandmetaanalysisofcontrolledclinicaltrials