Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report

Glomus tumors (GTs) are rare mesenchymal neoplasms that occur predominantly on the subungual region of the distal extremities and are rarely seen in visceral organs such as the gastrointestinal tract. Malignant glomus tumors (MGTs) is even more rare, comprising less than 1% of all GTs. We reported a...

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Main Authors: Shilan Peng, Nan Yang, Zifan Xu, Guomiao Su, Xiaoyu Tuo, Shiyue Liu, Zi Lei, Guoqing Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1519968/full
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author Shilan Peng
Nan Yang
Zifan Xu
Guomiao Su
Xiaoyu Tuo
Shiyue Liu
Zi Lei
Guoqing Pan
author_facet Shilan Peng
Nan Yang
Zifan Xu
Guomiao Su
Xiaoyu Tuo
Shiyue Liu
Zi Lei
Guoqing Pan
author_sort Shilan Peng
collection DOAJ
description Glomus tumors (GTs) are rare mesenchymal neoplasms that occur predominantly on the subungual region of the distal extremities and are rarely seen in visceral organs such as the gastrointestinal tract. Malignant glomus tumors (MGTs) is even more rare, comprising less than 1% of all GTs. We reported an 82-year-old female patient with MGTs of the jejunum, accompanied by metastases to the liver and peritoneum. The patient presented with a primary complaint of epigastric pain with nausea and acid reflux for two months. Computed tomography scan revealed a prominently enhanced, inhomogeneous-density mass in the jejunum, the nature of which—benign or malignant—could not initially be determined. Postoperative pathological diagnosis confirmed the lesion to be a jejunal MGT. Regrettably, the patient declined additional treatment, subsequently developing liver and peritoneal metastases one year later. She eventually died within 18 months of initial diagnosis. This report summarizes the clinical and histopathological features of jejunal MGTs with the aim of increasing awareness among clinicians and pathologists regarding this disease.
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publishDate 2025-01-01
publisher Frontiers Media S.A.
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spelling doaj-art-731390fd1d4c45d1bc8ef7d989fcff902025-01-17T09:21:57ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.15199681519968Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case reportShilan Peng0Nan Yang1Zifan Xu2Guomiao Su3Xiaoyu Tuo4Shiyue Liu5Zi Lei6Guoqing Pan7Department of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, ChinaCollege of The First Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, ChinaDepartment of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, ChinaDepartment of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, ChinaDepartment of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, ChinaDepartment of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, ChinaDepartment of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, ChinaDepartment of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, ChinaGlomus tumors (GTs) are rare mesenchymal neoplasms that occur predominantly on the subungual region of the distal extremities and are rarely seen in visceral organs such as the gastrointestinal tract. Malignant glomus tumors (MGTs) is even more rare, comprising less than 1% of all GTs. We reported an 82-year-old female patient with MGTs of the jejunum, accompanied by metastases to the liver and peritoneum. The patient presented with a primary complaint of epigastric pain with nausea and acid reflux for two months. Computed tomography scan revealed a prominently enhanced, inhomogeneous-density mass in the jejunum, the nature of which—benign or malignant—could not initially be determined. Postoperative pathological diagnosis confirmed the lesion to be a jejunal MGT. Regrettably, the patient declined additional treatment, subsequently developing liver and peritoneal metastases one year later. She eventually died within 18 months of initial diagnosis. This report summarizes the clinical and histopathological features of jejunal MGTs with the aim of increasing awareness among clinicians and pathologists regarding this disease.https://www.frontiersin.org/articles/10.3389/fonc.2024.1519968/fulljejunummalignantglomus tumorcase reportdiagnose
spellingShingle Shilan Peng
Nan Yang
Zifan Xu
Guomiao Su
Xiaoyu Tuo
Shiyue Liu
Zi Lei
Guoqing Pan
Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report
Frontiers in Oncology
jejunum
malignant
glomus tumor
case report
diagnose
title Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report
title_full Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report
title_fullStr Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report
title_full_unstemmed Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report
title_short Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report
title_sort malignant glomus tumor of jejunum with liver and peritoneum metastasis a rare case report
topic jejunum
malignant
glomus tumor
case report
diagnose
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1519968/full
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