Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review
Purpose: To report the case of a male with a deep stromal corneal abscess recalcitrant to topical treatment who presented complete resolution after serial intrastromal broad-spectrum antibiotics injections. Observations: A 66 years old man with a medical history of type 1- neurofibromatosis presente...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | The Pan-American Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/pajo.pajo_80_24 |
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| _version_ | 1846123026973720576 |
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| author | Valentina Cárdenas Arias Jorge Rafael Mendez Marulanda |
| author_facet | Valentina Cárdenas Arias Jorge Rafael Mendez Marulanda |
| author_sort | Valentina Cárdenas Arias |
| collection | DOAJ |
| description | Purpose:
To report the case of a male with a deep stromal corneal abscess recalcitrant to topical treatment who presented complete resolution after serial intrastromal broad-spectrum antibiotics injections.
Observations:
A 66 years old man with a medical history of type 1- neurofibromatosis presented with a 1 1-month history of painful vision loss in his right eye. Ophthalmological examination showed a deep limbal corneal abscess with hypopyon, with a best corrected visual acuity of hand movements. The abscess was refractory to complete topical treatment. He underwent 4 interventions with intrastromal injections of 1mg/0.1ml vancomycin and ceftazidime with 15-day intervals each one, associated anterior chamber washout. A complete resolution of infection was established due to clinical and paraclinical improvement evidenced in serial anterior chamber tomographies.
Conclusion:
Treatment of bacterial deep corneal abscess is challenging because of the limited treatment options. There is a lack of evidence about standardized doses of intrastromal injection of antibiotics. |
| format | Article |
| id | doaj-art-730c935406d34d2295ff5f87448ea5a1 |
| institution | Kabale University |
| issn | 2666-4909 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Pan-American Journal of Ophthalmology |
| spelling | doaj-art-730c935406d34d2295ff5f87448ea5a12024-12-14T09:28:03ZengWolters Kluwer Medknow PublicationsThe Pan-American Journal of Ophthalmology2666-49092024-11-016311311310.4103/pajo.pajo_80_24Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature reviewValentina Cárdenas AriasJorge Rafael Mendez MarulandaPurpose: To report the case of a male with a deep stromal corneal abscess recalcitrant to topical treatment who presented complete resolution after serial intrastromal broad-spectrum antibiotics injections. Observations: A 66 years old man with a medical history of type 1- neurofibromatosis presented with a 1 1-month history of painful vision loss in his right eye. Ophthalmological examination showed a deep limbal corneal abscess with hypopyon, with a best corrected visual acuity of hand movements. The abscess was refractory to complete topical treatment. He underwent 4 interventions with intrastromal injections of 1mg/0.1ml vancomycin and ceftazidime with 15-day intervals each one, associated anterior chamber washout. A complete resolution of infection was established due to clinical and paraclinical improvement evidenced in serial anterior chamber tomographies. Conclusion: Treatment of bacterial deep corneal abscess is challenging because of the limited treatment options. There is a lack of evidence about standardized doses of intrastromal injection of antibiotics.https://journals.lww.com/10.4103/pajo.pajo_80_24case reportcorneal abscessintrastromal injections |
| spellingShingle | Valentina Cárdenas Arias Jorge Rafael Mendez Marulanda Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review The Pan-American Journal of Ophthalmology case report corneal abscess intrastromal injections |
| title | Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review |
| title_full | Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review |
| title_fullStr | Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review |
| title_full_unstemmed | Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review |
| title_short | Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review |
| title_sort | successful treatment of deep corneal abscess with serial intrastromal broad spectrum antibiotic injection case report and literature review |
| topic | case report corneal abscess intrastromal injections |
| url | https://journals.lww.com/10.4103/pajo.pajo_80_24 |
| work_keys_str_mv | AT valentinacardenasarias successfultreatmentofdeepcornealabscesswithserialintrastromalbroadspectrumantibioticinjectioncasereportandliteraturereview AT jorgerafaelmendezmarulanda successfultreatmentofdeepcornealabscesswithserialintrastromalbroadspectrumantibioticinjectioncasereportandliteraturereview |